Invitrogen™ ZDHHC20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116796

Catalog No. PIPA5116796

Description

Positive Samples: HeLa, MCF7, SKOV3, A-549, Mouse brain, Mouse lung, Mouse testis, Rat brain, Rat lung Immunogen sequence: VFGDEKKYWL LPIFSSLGDG CSFPTRLVGM DPEQASVTNQ NEYARSSGSN QPFPIKPLSE SKNRLLDSES QWLENGAEEG IVKSGTNNHV TVAIEN.

Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245). [UniProt].

Specifications

• Antigen: ZDHHC20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZDHHC20
• Gene Alias: 4933421L13Rik; 5033406L14Rik; AI448102; B230110O18Rik; DHHC-20; DHHC-containing protein 20; HK11; membrane-associated DHHC24 zinc finger protein; Palmitoyltransferase ZDHHC20; probable palmitoyltransferase ZDHHC20; RGD1305755; ZDHHC20; Zinc finger DHHC domain-containing protein 20; zinc finger DHHC-type containing 20; zinc finger, DHHC domain containing 20; zinc finger, DHHC-type containing 20
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 253832, 305923, 75965
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5W0Z9, Q5Y5T1
• Gene Symbols: ZDHHC20
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 270-365 of human ZDHHC20 (NP_0013169881).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov