ZFAND1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA551173
The antibody detects endogenous levels of total ZFAND1 protein.Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFAND1 (AN1-type zinc finger protein 1) is a 268 amino acid protein that contains 2 AN1-type zinc fingers, which are often found in proteins that contain a ubiquitin-like domain and therefore play a role in the ubiquitination pathway. AN1-type zinc fingers contains six conserved cysteines and two histidines and have a dimetal (zinc)-bound alpha/beta fold. There are two isoforms of ZFAND1 that are produced as a result of alternative splicing events.
|Full length fusion protein of human ZFAND1|
|Antigen affinity chromatography|
|PBS with 40% glycerol and 0.05% sodium azide; pH 7.4|
|AN1-type zinc finger protein 1, FLJ14007, ZFAN1, ZFAND1, zinc finger, AN1-type domain 1|
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