ZFP36 Monoclonal Antibody (OTI1C8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502384

Catalog No. 50-167-3445

Description

ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.

Specifications

• Antigen: ZFP36
• Classification: Monoclonal
• Concentration: 0.95 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P26651
• Gene Symbols: ZFP36
• Immunogen: Full length human recombit protein of human ZFP36 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1C8
• Conjugate: Unconjugated
• Gene: ZFP36
• Gene Alias: G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7538
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid