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ZFP36 Mouse anti-Human, Clone: OTI3H1, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502380

Catalog No. 50-167-3441



Description

Description

ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
Specifications

Specifications

ZFP36
Monoclonal
0.6 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P26651
G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7538
Flow Cytometry, Western Blot
OTI3H1
Unconjugated
ZFP36
Liquid
ZFP36
Full length human recombit protein of human ZFP36 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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