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ZFYVE21 Mouse anti-Human, Clone: OTI2B12, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA505606

Catalog No. 50-167-6052


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Description

Description

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
Specifications

Specifications

ZFYVE21
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9BQ24
HCVP7TP1, ZF21
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79038
Western Blot
OTI2B12
Unconjugated
ZFYVE21
Liquid
ZFYVE21
Full length human recombit protein of human ZFYVE21 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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