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ZFYVE21 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 248061AP

Catalog No. 50-173-4555


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Description

Description

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
Specifications

Specifications

ZFYVE21
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9BQ24
ZFYVE21
Rabbit
IgG
150 μL
-20°C
Primary
79038
Immunoprecipitation, Western Blot
Unconjugated
ZFYVE21
Liquid
ZFYVE21
ZFYVE21 Fusion Protein Ag20024
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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