ZGPAT Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 232031AP
DescriptionTranscription repressor that specifically binds the 5 ft.-GGAG[GA]A[GA]A-3 ft. consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZGPAT, ZIP|
|ZGPAT Fusion Protein Ag19620|
|Antigen Affinity Chromatography|
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