Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Zika Virus NS1 Mouse anti-Virus, Clone: EA23, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524582

Catalog No. PIMA524582


Add to cart

Description

Description

MA5-24582 does not cross react with the following viruses: Dengue 1-4, TBE virus, West Nile virus, Yellow Fever virus, Japanese Encephalitis virus and Chikungunya virus.

As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. & Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.
Specifications

Specifications

Zika Virus NS1
Monoclonal
100 μg/mL
PBS with 0.1% sodium azide; pH 7.2
ZIKV NS1; ZIKV-NS1; Zika Nonstructural protein 1; Zika NS1
recombit Zika Virus NS1 protien
Protein A
RUO
Antibody
Monoclonal
ELISA, Immunocytochemistry, Immunofluorescence
EA23
Unconjugated
Liquid
Mouse
IgG1
100 μg
4° C
Primary
Virus
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit