ZIP4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 206251AP
DescriptionThe zinc transporter ZIP4, also known as SLC39A4, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP4 was initially identified as zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in the absorption of dietary zinc. Similar to other ZIP family members, aberrant expression of ZIP4 has been linked to cancer, specifically the progression and aggressiveness of pancreatic cancer. ZIP4 expression has also been shown to be activated in hepatocellular carcinomas, acting to repress apoptosis, enhance cell cycle and increase migration, suggesting ZIP4 may play a role in multiple types of cancers.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|AEZ, SLC39A4, Zinc transporter ZIP4, ZIP 4, ZIP4, Zrt and Irt like protein 4|
|Immunohistochemistry (Paraffin), Western Blot|
|ZIP4 Fusion Protein Ag14524|
|Antigen Affinity Chromatography|
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