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  7. ZK 200775, Tocris Bioscience™

ZK 200775, Tocris Bioscience™

Catalog Number 234550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
161605-73-8
C14H15F3N3O6P
409.258
WZMQMKNCWDCCMT-UHFFFAOYSA-N
fanapanel, mpqx, fanapanel inn, unii-e3ap71em0o, e3ap71em0o, 7-morpholin-4-yl-2,3-dioxo-6-trifluoromethyl-4h-quinoxalin-1-yl methylphosphonic acid, dsstox_cid_26093, dsstox_rid_81332, dsstox_gsid_46093, 3,4-dihydro-7-morpholino-2,3-dioxo-6-trifluoromethyl-1 2h-quinoxalinyl methyl phosphonic acid
208953
[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]methylphosphonic acid
C1COCCN1C2=CC3=C(C=C2C(F)(F)F)NC(=O)C(=O)N3CP(=O)(O)O
This item is not returnable. View return policy
161605-73-8
C14H15F3N3O6P
409.258
WZMQMKNCWDCCMT-UHFFFAOYSA-N
fanapanel, mpqx, fanapanel inn, unii-e3ap71em0o, e3ap71em0o, 7-morpholin-4-yl-2,3-dioxo-6-trifluoromethyl-4h-quinoxalin-1-yl methylphosphonic acid, dsstox_cid_26093, dsstox_rid_81332, dsstox_gsid_46093, 3,4-dihydro-7-morpholino-2,3-dioxo-6-trifluoromethyl-1 2h-quinoxalinyl methyl phosphonic acid
208953
[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]methylphosphonic acid
C1COCCN1C2=CC3=C(C=C2C(F)(F)F)NC(=O)C(=O)N3CP(=O)(O)O

Description

Competitive non-NMDA iGluR antagonist

Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo.
Quantity 50 mg
Formula Weight 409.25
Percent Purity >99%
Chemical Name or Material ZK 200775

Safety and Handling

Recommended Storage Desiccate at +4°C
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