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  8. ZK 756326, Tocris Bioscience™

ZK 756326, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1780259-94-0
C21H30Cl2N2O3
MPACCEKWFGWZHS-UHFFFAOYSA-N
zk756326 dihydrochloride, acmc-20p1e4, 2-2-4-3-phenoxyphenyl methyl piperazin-1-yl ethoxy ethanol dihydrochloride, 2-2-4-3-phenoxyphenyl methyl-1-piperazinyl ethoxy ethanol dihydrochloride
56972201
This item is not returnable. View return policy
1780259-94-0
C21H30Cl2N2O3
MPACCEKWFGWZHS-UHFFFAOYSA-N
zk756326 dihydrochloride, acmc-20p1e4, 2-2-4-3-phenoxyphenyl methyl piperazin-1-yl ethoxy ethanol dihydrochloride, 2-2-4-3-phenoxyphenyl methyl-1-piperazinyl ethoxy ethanol dihydrochloride
56972201

Description

Selective, non-peptide CCR8 agonist

Selective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
Quantity 10 mg
SMILES Cl.Cl.OCCOCCN1CCN(CC2=CC(OC3=CC=CC=C3)=CC=C2)CC1
IUPAC Name 2-(2-{4-[(3-phenoxyphenyl)methyl]piperazin-1-yl}ethoxy)ethan-1-ol dihydrochloride
Molecular Weight (g/mol) 429.38
Formula Weight 429.38
Percent Purity >99%
Chemical Name or Material ZK 756326

Safety and Handling

Recommended Storage : Desiccate at Room Temperature