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Tocris Bioscience™ ZM 336372

Potent, selective c-Raf inhibitor

Supplier:  Tocris Bioscience™ 1321/10

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Catalog No. 13-211-0

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

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Description

Description

ZM 336372 is a potent, selective inhibitor of c-Raf in vitro (IC50 = 70 nM for inhibition of human c-Raf). Shows 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC50 = 2 μM). Selective over 17 other protein kinases including PKA, PKC, p42 MAPK, CDK1 and SAPK1/JNK (up to 50 μM).
Specifications

Specifications

99%
208260-29-1
10 mg
M.W. (Observed): 389.45
3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
4°C
ZM 336372
ZM 336372
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