Tocris™ ZM 336372

Potent, selective c-Raf inhibitor

Manufacturer: Tocris™ 1321/50

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Catalog No. 13-215-0

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For Research Use Only


    Specifications

    Product Type ZM 336372
    Inhibitors ZM 336372
    Purity >99
    Molecular Weight 389.45
    Quantity 50mg

    Potent, selective inhibitor of c-Raf in vitro (IC50 = 70nM for inhibition of human c-Raf). Shows 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC50 = 2µM). Selective over 17 other protein kinases including PKA, PKC, p42 MAPK, CDK1 and SAPK1/JNK (up to 50µM). Also available as part of the MAPK Cascade Inhibitor Tocriset™.

    • Chemical Name: 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
    • Formula: C23H23N3O3
    • CAS Number: 208260-29-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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