Invitrogen™ ZMIZ2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531271

Catalog No. PIPA531271

Description

Recommended positive controls: IMR32. Predicted reactivity: Mouse (92%), Rat (93%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.

Specifications

• Antigen: ZMIZ2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZMIZ2
• Gene Alias: D11Bwg0280e; HRIHFB2007; hZIMP7; KIAA1886; NET27; PIAS-like protein Zimp7; TRAFIP20; Zimp7; zinc finger MIZ domain-containing protein 2; zinc finger MIZ-type containing 2; zinc finger, MIZ-type containing 2; Zmiz2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83637
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.93 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8NF64
• Gene Symbols: ZMIZ2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 569 and 818 of Human ZMIZ2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov