ZNF217 Mouse anti-Human, Clone: OTI2B1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527088
DescriptionZNF217, also known as ZABC1, is a zinc finger protein belonging to the Krüppel C2H2-type zinc-finger protein family. It localizes to the nucleus and may play a role in transcriptional repression of a variety of genes through the recruitment of co-repressor complexes containing proteins such as CtBP, HDAC1 and HDAC2. In addition, ZNF217 participates in cell differentiation and appears to function as an oncogene. Expression of ZNF217 is amplified in various tumors and overexpression of the protein can attenuate apoptotic signals and lead to epithelial cell immortalization.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Zinc finger protein 217; ZNF217; ZABC1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 730-1048 of ZNF217 produced in E.coli|
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