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ZNF268 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551177

Catalog No. PA551177


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Description

Description

The antibody detects endogenous levels of total ZNF268 protein.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events.
Specifications

Specifications

ZNF268
Polyclonal
Unconjugated
ZNF268
Liquid
ZNF268
Fusion protein of human ZNF268
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.9 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q14587
HZF3
Rabbit
IgG
100 μL
-20°C
Primary
10795
Documents
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