ZNF496 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 209001AP
DescriptionZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remt of a C2H2 motif.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|NIZP1, zinc finger protein 496, ZKSCAN17, ZNF496|
|ZNF496 Fusion Protein Ag15015|
|Antigen Affinity Chromatography|