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ZNF50 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550165

Catalog No. PA550165


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Description

Description

The antibody detects endogenous levels of total ZNF50 / ZSCAN22 protein.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.
Specifications

Specifications

ZNF50
Polyclonal
Unconjugated
ZSCAN22
Liquid
ZSCAN22
Synthesized peptide derived from internal of human ZSCAN22.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P10073
Zinc finger and SCAN domain-containing protein 22, Zinc finger protein 50, Krueppel-related zinc finger protein 2, Protein HKR2, ZSCAN22
Rabbit
IgG
100 μL
-20°C
Primary
342945
Documents
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