ZNF50 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550165
The antibody detects endogenous levels of total ZNF50 / ZSCAN22 protein.Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.
|Synthesized peptide derived from internal of human ZSCAN22.|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|Zinc finger and SCAN domain-containing protein 22, Zinc finger protein 50, Krueppel-related zinc finger protein 2, Protein HKR2, ZSCAN22|
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