ZNF711 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 251661AP
DescriptionCDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of the gene have been reported.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|CMPX1, Zfp711, Zinc finger protein 6, zinc finger protein 711, ZNF4, ZNF5, ZNF6, ZNF711|
|ZNF711 Fusion Protein Ag18309|
|Antigen Affinity Chromatography|
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