Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ZSCAN4 Mouse anti-Human, Clone: OTI1A6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526458

Catalog No. PIMA526458


Add to cart

Description

Description

Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintece and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.
Specifications

Specifications

ZSCAN4
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8NAM6
ZNF494; zinc finger and SCAN domain-containing protein 4; zinc finger protein 494
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
201516
Immunohistochemistry (Paraffin), Western Blot
OTI1A6
Unconjugated
ZSCAN4
Liquid
ZSCAN4
Human recombit protein fragment corresponding to amino acids 164-433 of ZSCAN4 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit