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ZSCAN4 Mouse anti-Canine, Human, Clone: OTI3B1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526446

Catalog No. PIMA526446



Description

Description

Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintece and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.
Specifications

Specifications

ZSCAN4
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8NAM6
ZNF494; zinc finger and SCAN domain-containing protein 4; zinc finger protein 494
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
106559239, 201516
Western Blot
OTI3B1
Unconjugated
ZSCAN4
Liquid
ZSCAN4
Human recombit protein fragment corresponding to amino acids 164-433 of ZSCAN4 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human
Documents
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