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See other NFE2L2 GE Assays ›
Gene Symbol:
Nfe2l2
Gene Name:
nuclear factor, erythroid derived 2, like 2
Gene Aliases:
AI194320, Nrf2
Chromosome Location:
Chr.2: 75675519 - 75704641 on Build GRCm38
Species:
Mouse
Species Specific ID (Flybase ID):
-
Assay ID Mm00477784_m1
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Catalog # 4331182
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  • Genomic Map
  • Assay Details
  • More Information
  • Citations (1)

Genomic Map

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Assay Details

Gene Symbol: Nfe2l2
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_010902.3 NP_035032.1 1 - 2 279 61
GenBank mRNA AK142347.1 - 1 - 2 181 61
AK144247.1 - 1 - 2 153 61
BC003340.1 - 1 - 2 135 61
BC026943.1 - 1 - 2 220 3663276 61
BY792550.1 - 1 - 2 279 61

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More Information


Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200003791.mm.1

Set Membership:

Ambion siRNA available Amplicon length less than or equal to 70 Mammalian Gene Collection Recommended Assay Mus musculus Inventoried Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nfe2l2

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Function(s) Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
inflammatory response
proteasomal ubiquitin-independent protein catabolic process
positive regulation of gene expression
protein ubiquitination
positive regulation of blood coagulation
endoplasmic reticulum unfolded protein response
cellular response to oxidative stress
response to endoplasmic reticulum stress
cellular response to drug
positive regulation of transcription from RNA polymerase II promoter in response to stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
PERK-mediated unfolded protein response
cellular response to glucose starvation
proteasome-mediated ubiquitin-dependent protein catabolic process
cell redox homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of embryonic development
negative regulation of cell death
cellular response to hydrogen peroxide
cellular response to tumor necrosis factor
cellular response to fluid shear stress
cellular response to laminar fluid shear stress
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced cell death
positive regulation of glutathione biosynthetic process
regulation of removal of superoxide radicals
negative regulation of endothelial cell apoptotic process
positive regulation of reactive oxygen species metabolic process
transcription regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription cofactor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
sequence-specific DNA binding
protein heterodimerization activity

MicroArray Probes:

Affymetrix

Array Name Probe IDs Targets Target Type
Affymetrix Mouse Clariom S Array PSR0200032405.mm.1 NM_010902.4 Refseq
Affymetrix Mouse Clariom S Array PSR0200032405.mm.1 TC0200003791.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR0200032407.mm.1 NM_010902.4 Refseq
Affymetrix Mouse Clariom S Array PSR0200032407.mm.1 TC0200003791.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR0200032408.mm.1 NM_010902.4 Refseq
Affymetrix Mouse Clariom S Array PSR0200032408.mm.1 TC0200003791.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR0200032409.mm.1 NM_010902.4 Refseq
Affymetrix Mouse Clariom S Array PSR0200032409.mm.1 TC0200003791.mm.1 MTA TC

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Citations (1)

An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.
Authors
Kaspar JW, Jaiswal AK
Journal
J Biol Chem - Page No 21349 (Fri Jul 09 00:00:00 UTC 2010)
Volume (Year)
285 (2010)
Product Usage
-

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