Custom Enzymes and Inhibitors

Thermo Scientific™ EpiJET™ Bisulfite Conversion Kit

The EpiJET Bisulfite Conversion Kit is used for an efficient bisulfite modification of DNA for methylation analysis.

Tocris™ PMX 464

Putative inhibitor of the Trx-TrxR system; antiproliferative

Tocris™ AZD 7762 hydrochloride

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2

Tocris™ CRT 0066101

Potent protein kinase D (PKD) inhibitor

R&D Systems clasto-Lactacystin beta Lactone

Potent, highly specific, irreversible and cell-permeable inhibitor that covalently modifies the beta subunits of the proteasome

Tocris™ 5,7-Dichlorokynurenic acid sodium salt

Sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286). Potent NMDA antagonist, acts at glycine site

Tocris™ XAP 044

Potent and selective mGlu7 antagonist

Tocris™ STO-609 acetate

Selective CaM kinase kinase inhibitor

Tocris™ Salvinorin A

Highly potent and selective kappa agonist

Tocris™ Bromophenol Blue

Dye used in gel loading buffers

Tocris™ Cystamine dihydrochloride

Transglutaminase inhibitor; neuroprotective

Tocris™ ZD 7155 hydrochloride

Selective non-peptide AT1 antagonist

Tocris™ MRS 2500 tetraammonium salt

Extremely potent and selective P2Y1 antagonist

Tocris™ Neuropathiazol

Selective inducer of neuronal differentiation in hippocampal neural progenitors

Tocris™ CK 869

Arp2/3 inhibitor; inhibits actin polymerization

Tocris™ AS 1949490

SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor

Tocris™ GBR 12909 dihydrochloride

Selective DA uptake inhibitor. Also sigma ligand

Tocris™ L-Glutathione Reduced

Endogenous antioxidant

Tocris™ PS 1145 dihydrochloride

Selective IKK inhibitor; orally active

Tocris™ INDY

DYRK1A/B inhibitor

Tocris™ ML 337

Selective negative allosteric modulator of mGlu3

Tocris™ STF 118804

NAMPT inhibitor

Tocris™ FK 506

Potent calcineurin inhibitor; immunosuppressant

Tocris™ BMS 195614

Selective RARalpha antagonist

Tocris™ DCG IV

Very potent, selective group II mGlu agonist. Also NMDA agonist

Tocris™ (RS)-(Tetrazol-5-yl)glycine

Highly potent NMDA receptor agonist

Tocris™ SR 3576

Highly potent and selective JNK3 inhibitor

Tocris™ AI-3

ARE activator; induces Nrf2-ARE-dependent transcription

Tocris™ NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic