Custom Enzymes and Inhibitors

Thermo Scientific™ EpiJET™ Bisulfite Conversion Kit

The EpiJET Bisulfite Conversion Kit is used for an efficient bisulfite modification of DNA for methylation analysis.

R&D Systems b-AP15/VLX1500

Specifically inhibits the 19S regulatory particle-associated deubiquitinases USP14 and UCHL5, resulting in the accumulation of intracellular polyubiquitin

Tocris™ GSK 2606414

Potent and selective PERK inhibitor; orally bioavailable

Tocris™ Mibefradil dihydrochloride

Ca2+ channel blocker (T-type)

R&D Systems PS-341, 26S Proteasome Inhibitor

A potent, specific, and reversible proteasome inhibitor

Tocris™ VU 0361737

Selective positive allosteric modulator at mGlu4

Tocris™ SB 657510

Selective urotensin-II (UT) receptor antagonist

Tocris™ ML 786 dihydrochloride

Potent Raf kinase inhibitor; orally bioavailable

Tocris™ (RS)-MCPG disodium salt

Sodium salt of (RS)-MCPG (Cat. No. 0336)

Tocris™ E 64

Potent and irreversible cysteine protease inhibitor

Tocris™ DBM 1285 dihydrochloride

p38 MAPK inhibitor; anti-inflammatory

Tocris™ 5-BrdU

Synthetic thymidine analog; used for cell proliferation assays

Tocris™ CP 376395 hydrochloride

Potent and selective CRF1 antagonist

Tocris™ ZM 226600

Kir6 (KATP) channel opener

Tocris™ AL 8697

Potent and selective p38alpha inhibitor

Tocris™ ABT 724 trihydrochloride

Potent, selective D4 partial agonist; proerectile

Tocris™ TAK 165

Potent and selective ErbB2 inhibitor

Tocris™ K 858

Selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor

Tocris™ LIMKi 3

Potent LIM kinase inhibitor; antitumor

Tocris™ GBR 12909 dihydrochloride

Selective DA uptake inhibitor. Also sigma ligand

Tocris™ Efonidipine hydrochloride monoethanolate

Ca2+ channel blocker (L- and T-type)

Tocris™ Potassium phosphate monobasic

Commonly used in biological assay buffers

Tocris™ PD 98059

MEK inhibitor

Tocris™ D-AP4

Broad spectrum EAA antagonist

Tocris™ SIB 1893

mGlu5 antagonist and positive allosteric modulator at mGlu4

Tocris™ PIM-1 Inhibitor 2

Pim-1 kinase inhibitor

Tocris™ R 59-022

Diacylglycerol kinase inhibitor; increases PKC activity

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