Custom Enzymes and Inhibitors

Tocris Bioscience™ Prostaglandin F2α

Naturally-occurring prostanoid; potent vasoconstrictor

BD General Caspase Inhibitor, Z-VAD-FMK Available on GSA/VA Contract for Federal Government customers only.

Cell permeable general caspase inhibitor that binds to the catalytic site of caspase proteases irreversibly and inhibits apoptosis

R&D Systems™ proTAME Available on GSA/VA Contract for Federal Government customers only.

Cell-permeable APC/C inhibitor

Tocris Bioscience™ LL 37

Antimicrobial peptide derivative of human cathelicidin

Tocris Bioscience™ DL-AP5 Sodium salt Available on GSA/VA Contract for Federal Government customers only.

Sodium salt of DL-AP5 (Cat. No. 0105)

Novus Biologicals™ MyD88 Inhibitor Peptide Set

For use in research applications

Tocris Bioscience™ Latrunculin A Available on GSA/VA Contract for Federal Government customers only.

Inhibitor of actin assembly and polymerization

Tocris Bioscience™ CP 376395 hydrochloride Available on GSA/VA Contract for Federal Government customers only.

Potent and selective CRF1 antagonist

Tocris Bioscience™ ATPγS Tetralithium Salt Available on GSA/VA Contract for Federal Government customers only.

P2 agonist; ATP (Cat. No. 3245) analog

Tocris Bioscience™ AR-C155858 Available on GSA/VA Contract for Federal Government customers only.

MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells

Tocris Bioscience™ Allopregnanolone Available on GSA/VA Contract for Federal Government customers only.

GABAA receptor positive allosteric modulator

Tocris Bioscience™ SB 204990 Available on GSA/VA Contract for Federal Government customers only.

ATP citrate lyase (ACLY) inhibitor

Tocris Bioscience™ GSK 2837808A Available on GSA/VA Contract for Federal Government customers only.

Potent, selective LDHA inhibitor

Tocris Bioscience™ Teriflunomide

Dihydroorotate dehydrogenase inhibitor

Tocris Bioscience™ CHPG Sodium salt Available on GSA/VA Contract for Federal Government customers only.

Selective mGlu5 agonist. Sodium salt of CHPG (Cat. No. 1049)

Tocris Bioscience™ FK 506

Potent calcineurin inhibitor; immunosuppressant

Tocris Bioscience™ LY 379268 disodium salt Available on GSA/VA Contract for Federal Government customers only.

Sodium salt of LY 379268 (Cat. No. 2453); selective group II mGlu receptor agonist

Tocris Bioscience™ EC 144 Available on GSA/VA Contract for Federal Government customers only.

High affinity, potent and selective Hsp90 inhibitor

Tocris Bioscience™ DS2

Positive allosteric modulator of δ-containing GABAA receptors

Tocris Bioscience™ MRS 2500 tetraammonium salt Available on GSA/VA Contract for Federal Government customers only.

Extremely potent and selective P2Y1 antagonist

Tocris Bioscience™ E 64 Available on GSA/VA Contract for Federal Government customers only.

Potent and irreversible cysteine protease inhibitor

Tocris Bioscience™ Tautomycetin

Selective PP1 inhibitor

Tocris Bioscience™ NU 7441 Available on GSA/VA Contract for Federal Government customers only.

Potent and selective DNA-PK inhibitor

Tocris Bioscience™ Tetrabenazine Available on GSA/VA Contract for Federal Government customers only.

Potent inhibitor of vesicular monoamine transport

R&D Systems™ Epoxomicin

Cell-permeable, potent, selective and irreversible proteasome inhibitor

Tocris Bioscience™ API-2 Available on GSA/VA Contract for Federal Government customers only.

Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

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