Custom Services and Products

R&D Systems VersaClone cDNA, Human Activin RIB/ALK-4 (NP_004293)

Mutations in ACVR1B are associated with pituitary tumors. Alternatively spliced transcripts encoding different proteins have been described

Tocris™ Fenretinide - d4

Deuterated fenretinide (Cat. No. 1396)

R&D Systems VersaClone cDNA, Human LILRB5/CD85c/LIR-8 (NP_006831)

Also known as CD85c and LIR-8. This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation.

Tocris™ Fluoxetine - d5 hydrochloride

Deuterated fluoxetine (Cat. No. 0927)

BD Caspase-9 Inhibitor, Z-LEHD-FMK Available on GSA/VA Contract for Federal Government customers only.

Irreversible and cell permeable inhibitor of caspase-9

R&D Systems VersaClone cDNA, Mouse FGF R3 (NP_032036)

FGFR3 plays an essential role in the regulation of cell proliferation, differentiation, and apoptosis

R&D Systems VersaClone cDNA, Human IL-12 R beta 1 (NP_005526)

IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35

Tocris™ Tomoxetine - d3 hydrochloride

Deuterated tomoxetine (Cat. No. 2011)

R&D Systems VersaClone cDNA, Human MFAP3L (NP_067679)

Microfibrillar-Associated Protein 3-Like

R&D Systems VersaClone cDNA, Human GABA-A R epsilon (NP_004952)

GABA-A receptors are heteropentamer combinations of seven subunit types

R&D Systems VersaClone cDNA, Mouse B7-H3 (NP_598744)

B7-H3 has been shown to bind an unidentified counter-receptor on activated T cells to costimulate the proliferation of CD4+ or CD8+ T cells

R&D Systems Human ECSCR (NP_001071161) VersaClone cDNA

Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator

Tocris™ HNGF6A

Humanin analog; increases insulin sensitivity

R&D Systems VersaClone cDNA, Human CD1a (AAA51931)

The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands

R&D Systems Human LILRA3/CD85e (NP_006856) VersaClone cDNA

Leucocyte immunoglobulin-like receptor

R&D Systems Z-Leu-Leu-Phe-CHO (Z-LLF-CHO)

Reversible, cell-permeable chymotrypsin-like peptidase inhibitor of the 20S proteasome

R&D Systems VersaClone cDNA, Human LILRB4/CD85k/ILT3 (NP_001265355)

'Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 4

Tocris™ Memantine - d6 hydrochloride

Deuterated memantine (Cat. No. 0773)

Tocris™ Nociceptin

Endogenous NOP agonist

R&D Systems VersaClone cDNA, Human G-CSF R/CD114 (NP_000751)

Mutations in G-CSFR are a cause of Kostmann syndrome, also known as severe congenital neutropenia

R&D Systems VersaClone cDNA, Human Plexin A4 (NP_065962)

PLXNA4 regulates cell migration, activation, and axon guidance via repulsion.

R&D Systems VersaClone cDNA, Mouse B7-H2 (NP_056605)

B7-H2 may play an important role in mediating local tissue responses to inflammatory conditions

Tocris™ Metformin - d6 hydrochloride

Deuterated metformin (Cat. No. 2864)

Tocris™ TAK 960 hydrochloride

Potent and selective PLK1 inhibitor