Custom Services and Products

Thermo Scientific™ EpiJET™ Bisulfite Conversion Kit

The EpiJET Bisulfite Conversion Kit is used for an efficient bisulfite modification of DNA for methylation analysis.

R&D Systems VersaClone cDNA, Human Plexin A4 (NP_065962)

PLXNA4 regulates cell migration, activation, and axon guidance via repulsion.

Tocris™ AP 811

High affinity, selective NPR3 antagonist

Tocris™ Norleual

Highly potent HGF/c-MET inhibitor; also AT4 antagonist

Tocris™ Citalopram - d4 hydrobromide

Deuterated citalopram (Cat. No. 1427)

R&D Systems VersaClone cDNA, Mouse PD-L2/B7-DC (NP_067371)

The extracellular domains of mouse and human PD-L2 share approximately 72% amino acid sequence identity

R&D Systems Epoxomicin

Cell-permeable, potent, selective and irreversible proteasome inhibitor

R&D Systems VersaClone cDNA, Human BMPR-IB/ALK-6 (NP_001194)

BMPR1B is expressed in various tissues during embryogenesis. In adult tissues, BMPR1B is only found in the brain

R&D Systems Human ALCAM/CD166 (NP_001618) VersaClone cDNA

Activated Leukocyte Cell Adhesion Molecule

Tocris™ Tomoxetine - d3 hydrochloride

Deuterated tomoxetine (Cat. No. 2011)

Tocris™ SirReal 2

Selective inhibitor of SIRT2

R&D Systems Mouse VSIG8 (NP_808391) VersaClone cDNA

V-set and immunoglobulin domain containing 8

R&D Systems Me4BodipyFL-Ahx3Leu3VS (Proteasome Activity Probe)

A cell-permeable fluorescent proteasome activity probe for accurate profiling of proteasomal activity in cell lysates, intact cells, and murine and human patient-derived material, with high sensitivity

Tocris™ 968

Allosteric inhibitor of glutaminase

R&D Systems VersaClone cDNA, Human IL-12 R beta 2 (NP_001550)

IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35

Tocris™ SLIGRL-NH2

PAR2-activating peptide

R&D Systems VersaClone cDNA, Human IL-27 R alpha/WSX-1/TCCR (NP_004834)

IL27RA is involved in the regulation of Th1 type immune responses. It may also be involved in innate defense mechanisms

R&D Systems Human Hepsin (NP_002142) VersaClone cDNA

Serine protease hepsin catalytic chain

R&D Systems VersaClone cDNA, Mouse Flt-3/Flk-2 (NP_034359)

FLT3 is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor

R&D Systems Mouse TGF-beta RII (NP_033397) VersaClone cDNA

Transforming Growth Factor beta Receptor II

Tocris™ Donepezil - d5 hydrochloride

Deuterated donepezil (Cat. No. 4385)

Tocris™ Flupirtine - d4 hydrochloride

Deuterated flupirtine (Cat. No. 2867)

R&D Systems b-AP15/VLX1500

Specifically inhibits the 19S regulatory particle-associated deubiquitinases USP14 and UCHL5, resulting in the accumulation of intracellular polyubiquitin

Tocris™ Foxy 5

Wnt5a peptide mimetic

R&D Systems VersaClone cDNA, Human IL-9 R (NP_002177)

IL9R is expressed in T cells, neutrophils, mast cells, and macrophages. It may be associated with the development of asthma. Alternatively splices transcripts encoding different proteins have been described

R&D Systems Human SLC6A8 (NP_005620) VersaClone cDNA

Creatine Transporter 1, CCDS1, CHOT1