Crosslinking, Labeling and Protein Modification

Thermo Scientific™ EZ-Link™ Maleimide PEG11-Biotin

Biotinylate reduced cysteines with this long, maleimide-activated, sulfhydryl-reactive biotinylation reagent with an 11-unit PEG spacer arm to enhance solubility and reach.

Thermo Scientific™ Pierce™ Methyl-PEG-NHS-Ester Reagents

Pegylate amines (-NH2 groups) on proteins (lysine residues) or assay surfaces using MS(PEG)n, amine-reactive (NHS ester), methyl-capped PEG compounds (4 to 24 EG units).

Thermo Scientific™ DyLight™ 550 2xPEG NHS Ester

PEGylated dye for enhanced fluorescence and reduced non-specific binding.

Thermo Scientific™ DyLight™ Near-IR Specialty Dyes

Label amine-containing molecules for fluorescence imaging or flow cytometry with these benzopyrillium- and cyanine-based, infrared-emitting (633 or 700 laser) NHS ester dyes.

Thermo Scientific™ EZ-Link™ Sulfo-NHS-Biotin and Labeling Kits

Biotinylate protein amines (e.g., lysines) with our shortest (13.5A), water-soluble, NHS-ester biotinylation reagent for antibody or cell-surface labeling.

Thermo Scientific™ EZ-Link™ Hydrazide-Biocytin

Biotinylate glycoproteins (aldehydes of oxidized sugars) with this short (19.7A) hydrazide-activated biotinylation reagent which also contains a second amine for conjugation.

Thermo Scientific™ DyLight™ Amine-Reactive Fluorescent Dyes

Label antibodies or other proteins as probes for fluorescence imaging assays with the full spectral range of NHS ester-activated DyLight Dyes.

Thermo Scientific™ Pierce™ TRITC Rhodamine Dyes and Labeling Kits

Label antibodies, proteins and other molecules for fluorescence imaging (ex 546; em 572-615) using these activated derivatives of red-fluorescent rhodamine dye.

Thermo Scientific™ EZ-Link™ Sulfo-NHS-LC-Biotin and Labeling Kits Available on GSA/VA Contract for Federal Government customers only.

Biotinylate protein amines (e.g., lysines) with this very popular mid-length (22.4A), water-soluble, NHS-ester biotinylation reagent for antibody or cell-surface labeling.

Thermo Scientific™ Pierce™ Methyl-PEG-Maleimide Reagents

Pegylate sulfhydryls (-SH groups) on proteins (cysteine residues) or assay surfaces using MS(PEG); sulfhydryl-reactive (maleimide), PEG compounds (12 and 24 EG units).

Thermo Scientific™ EZ-Link™ Biocytin

Synthesize long or trifunctional biotinylation reagents using this biotin variant containing a primary amine in its valeric acid chain.

Thermo Scientific™ Pierce™ SM(PEG)n Crosslinkers

Crosslink amines to sulfhydryls with these crosslinkers containing NHS-ester and maleimide groups at ends of water-soluble polyethylene glycol spacer arms (17.6 to 95.2A).

Thermo Scientific™ DyLight™ Sulfhydryl-Reactive Fluorescent Dyes

Label antibodies or other proteins as probes for fluorescence imaging assays with the full spectral range of maleimide-activated DyLight Dyes.

Thermo Scientific™ Pierce™ Sulfo-LC-SPDP Crosslinker

Crosslink amines to sulfhydryls with this water-soluble sulfo-NHS-ester and pyridyldithiol groups on 10-atom spacer arms to form cleavable disulfide bonds with cysteines.

Thermo Scientific™ DyLight™ Yellow Specialty Dyes

Label amine-containing molecules for fluorescence imaging or flow cytometry with these rhodamine-based, yellow-emitting (532 to 546 laser) NHS ester fluorescent dyes.

Thermo Scientific™ Pierce™ Azido-Sugars

Study glycoproteins using in vivo metabolic labeling and chemoselective ligation to phosphine reagents with these azide-tagged sugars (GlcNAz, GalNAz, ManNAz).

Thermo Scientific™ Pierce™ Carboxy-PEG-Amine Compounds

CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.

Thermo Scientific™ Pierce™ EDC Crosslinker

Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.

Thermo Scientific™ Pierce™ R-Phycoerythrin Fluorescent Protein

Create fluorescent probes (em 480, 545, 565; ex 578) using this red-fluorescent, multi-subunit protein that can be crosslinked or conjugated to other molecules.

Thermo Scientific™ EZ-Link™ Sulfo-NHS-SS-Biotin and Labeling Kits

Biotinylate protein amines with this cleavable, mid-length (24.3A), water-soluble, NHS-ester biotinylation reagent containing a cleavable disulfide bond in the spacer arm.

Thermo Scientific™ Pierce™ Sulfo-NHS-Acetate

Amine-reactive (NHS ester) compound to permanently block primary amines (e.g., protein lysine side chains) to prevent interactions or later conjugation.

Thermo Scientific™ EZ-Link™ TFP-PEG3-Biotin

Biotinylate primary amines (e.g., protein lysines) and secondary amines such as histidine and tryptophan with this tetrafluorophenyl-ester biotinylation reagent.

Thermo Scientific™ Pierce™ DST Crosslinker

Crosslink amines to amines with disuccinimidyl tartrate, composed of NHS-ester groups and a diol-containing spacer arm (6.4A) that is periodate-cleavable.

Thermo Scientific™ Pierce™ PMPI Crosslinker

Short (8.7A) hydroxyl-to-sulfhydryl crosslinker; isocyanate and maleimide groups; label -OH by urethane bonds for conjugation to cysteines by thioether bonds.

Thermo Scientific™ Pierce™ Sulfo-SMCC Crosslinker

Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.

Thermo Scientific™ Pierce™ BMB Crosslinker

Crosslink sulfhydryls to sulfhydryls (cysteine residues in proteins or peptides) with this mid-length crosslinker composed of maleimide groups and 9-atom (10.9A) spacer arm.

Thermo Scientific™ Pierce™ Immobilized Pepsin

Generate and purify Fab and F(ab')2 fragments from antibodies with acidic endopeptidase (pepsin) immobilized onto beaded agarose resin.

Thermo Scientific™ Pierce™ LC-SPDP Crosslinker

Crosslink amines to sulfhydryls with this crosslinker composed of NHS-ester and pyridyldithiol groups at ends of 10-atom (15.7A) spacer arm.

Thermo Scientific™ Pierce™ Premium Grade DSP

Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this popular amine-reactive, cleavable crosslinker.

Thermo Scientific™ DyLight™ Orange Specialty Dyes

Label amine-containing molecules for fluorescence imaging or flow cytometry with these rhodamine-based, orange-emitting (532 to 546 laser) NHS ester fluorescent dyes.

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