Hs00019165_cn

• Gene Symbol: PLA2G7
• Assay Reference Genome Location: Chr.6:46704629 on build GRCh38
• Cytoband: 6p12.3

Target Gene Details

• Entrez Gene ID: 7941
• Gene Name: phospholipase A2 group VII
• Gene Aliases: LDL-PLA2, LP-PLA2, PAFAD, PAFAH
• Location: Chr.6:46700954-46735836 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLA2G7	NM_001168357.1	12	1435	NP_001161829.1
	NM_005084.3	12	1526	NP_005075.3
	XM_005249408.4	12	1510	XP_005249465.1
	AK290381.1	12	1485
	BC038452.1	12	1435	AAH38452.1
	U20157.1	12	1418	AAC50126.1
	U24577.1	12	1473	AAB04170.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523148	Chr.6:46702199 - 46705206 on Build GRCh38	Loss	PLA2G7 TDRD6

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protein modifying enzyme

Gene Ontology Categories:

Process(es)

lipid catabolic process
low-density lipoprotein particle remodeling
lipid oxidation
plasma lipoprotein particle oxidation
positive regulation of inflammatory response
positive regulation of monocyte chemotaxis

Function(s)

1-alkyl-2-acetylglycerophosphocholine esterase activity
phospholipid binding
hydrolase activity, acting on ester bonds
calcium-independent phospholipase A2 activity