Hs00037400_cn

• Gene Symbol: FANCA
• Assay Reference Genome Location: Chr.16:89740112 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 2175
• Gene Name: Fanconi anemia complementation group A
• Gene Aliases: FA, FA-H, FA1, FAA, FACA, FAH, FANCH
• Location: Chr.16:89737551-89816658 on Build GRCh38
• Assay Gene Location: Overlaps Intron 40 - Exon 41

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FANCA	NM_000135.2			NP_000126.2
	NM_001286167.1			NP_001273096.1
	XM_005256294.4			XP_005256351.1
	XM_011522945.2			XP_011521247.1
	XM_011522946.2			XP_011521248.1
	XM_011522947.2			XP_011521249.1
	XM_017023044.1			XP_016878533.1
	AK299282.1
	AK301168.1
	X99226.1			CAA67610.1

Target Gene Details

• Entrez Gene ID: 92822
• Gene Name: zinc finger protein 276
• Gene Aliases: CENP-Z, CENPZ, ZADT, ZFP276, ZNF477
• Location: Chr.16:89720368-89740925 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF276	NM_001113525.1	11	3808	NP_001106997.1
	NM_152287.3	11	3798	NP_689500.2
	AK096004.1	1	1570
	BQ432535.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1931	Chr.16:89713649 - 89746701 on Build GRCh38	Insertion	VPS9D1 FANCA VPS9D1-AS1 ZNF276
nsv457624	Chr.16:89738447 - 89915950 on Build GRCh38	Loss	TCF25 LOC107984817 FANCA SPIRE2 ZNF276 LOC105371419
nsv952079	Chr.16:89685593 - 89749492 on Build GRCh38	Deletion	SPATA2L VPS9D1 FANCA VPS9D1-AS1 CDK10 ZNF276
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	DBNDD1 LOC107984817 VPS9D1 SPATA33 VPS9D1-AS1 AFG3L1P DEF8 GAS8-AS1 GAS8 CHMP1A CENPBD1 TCF25 DPEP1 SPATA2L TUBB3 FANCA CDK10 SPIRE2 ZNF276 MC1R LOC105371419
nsv457623	Chr.16:89664419 - 89853617 on Build GRCh38	Gain	SPATA2L LOC107984817 VPS9D1 SPATA33 FANCA VPS9D1-AS1 CDK10 SPIRE2 ZNF276 LOC105371419
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	DBNDD1 URAHP LOC107984817 SPATA33 AFG3L1P SPG7 TUBB8P7 GAS8 ZNF778 TCF25 SPATA2L CDK10 LOC100287036 ZNF276 MC1R LOC105371419 FAM157C PRDM7 SNORD68 VPS9D1 VPS9D1-AS1 LOC105371414 DEF8 GAS8-AS1 CHMP1A CENPBD1 DPEP1 TUBB3 ANKRD11 FANCA RPL13 LOC101927817 CPNE7 SPIRE2
nsv833331	Chr.16:89726091 - 89849806 on Build GRCh38	Gain+Loss	LOC107984817 FANCA SPIRE2 ZNF276 LOC105371419
nsv833330	Chr.16:89678466 - 89741783 on Build GRCh38	Loss	SPATA2L VPS9D1 FANCA VPS9D1-AS1 CDK10 ZNF276
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	DBNDD1 LOC100289580 LOC107984817 PABPN1L SPATA33 PIEZO1 AFG3L1P SPG7 TUBB8P7 SNAI3 SPATA2L MVD CDK10 LOC101927793 ZNF276 LOC339059 MC1R LOC400558 LOC105371419 FAM157C LOC100129697 CBFA2T3 CYBA LINC00304 SNORD68 IL17C LOC105371414 GAS8-AS1 DPEP1 TUBB3 FANCA LOC107987238 LOC101927817 CPNE7 GALNS URAHP CDH15 LOC105371409 GAS8 SNAI3-AS1 ZNF778 TCF25 CDT1 SLC22A31 LOC100287036 MIR4722 PRDM7 ACSF3 VPS9D1 VPS9D1-AS1 RNF166 CTU2 DEF8 APRT CHMP1A CENPBD1 ANKRD11 RPL13 TRAPPC2L SPIRE2
nsv509639	Chr.16:89513538 - 89775915 on Build GRCh38	Insertion	SNORD68 VPS9D1 SPATA33 VPS9D1-AS1 SPG7 CHMP1A DPEP1 SPATA2L FANCA RPL13 CDK10 CPNE7 ZNF276

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

DNA repair
protein complex assembly
male meiosis
male gonad development
female gonad development
interstrand cross-link repair
regulation of cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated

Function(s)

protein binding
DNA binding
zinc ion binding