Hs00055630_cn

• Gene Symbol: FANCA
• Assay Reference Genome Location: Chr.16:89737703 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 2175
• Gene Name: Fanconi anemia complementation group A
• Gene Aliases: FA, FA-H, FA1, FAA, FACA, FAH, FANCH
• Location: Chr.16:89737551-89816658 on Build GRCh38
• Assay Gene Location: Within Exon 44

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FANCA	NM_000135.2	43	5308	NP_000126.2
	NM_001286167.1	43	5312	NP_001273096.1
	X99226.1	43	5297	CAA67610.1

Target Gene Details

• Entrez Gene ID: 92822
• Gene Name: zinc finger protein 276
• Gene Aliases: CENP-Z, CENPZ, ZADT, ZFP276, ZNF477
• Location: Chr.16:89720368-89740925 on Build GRCh38
• Assay Gene Location: Overlaps Intron 12 - Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF276	NM_001113525.1			NP_001106997.1
	NM_152287.3			NP_689500.2
	NR_110122.1
	NR_110126.1
	NR_110128.1
	NR_110129.1
	XM_005256324.3			XP_005256381.1
	XM_005256328.3			XP_005256385.1
	XM_017023890.1			XP_016879379.1
	AK026482.1
	AK056405.1
	AK096762.1
	AK289801.1
	AK295770.1
	AK315793.1
	BC032781.1			AAH32781.2
	BC107603.1			AAI07604.1
	BC110348.1			AAI10349.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952079	Chr.16:89685593 - 89749492 on Build GRCh38	Deletion	VPS9D1-AS1 CDK10 FANCA ZNF276 SPATA2L VPS9D1
dgv872e212	Chr.16:89731232 - 89738373 on Build GRCh38	Loss	FANCA ZNF276
nsv573743	Chr.16:89664419 - 89853617 on Build GRCh38	Gain	VPS9D1-AS1 CDK10 LOC105371419 FANCA SPATA33 ZNF276 LOC107984817 SPATA2L SPIRE2 VPS9D1
nsv833330	Chr.16:89678466 - 89741783 on Build GRCh38	Loss	VPS9D1-AS1 CDK10 FANCA ZNF276 SPATA2L VPS9D1
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	FANCA CBFA2T3 ACSF3 LOC100289580 RPL13 CYBA ZNF778 VPS9D1 CDK10 LOC400558 PIEZO1 APRT LOC105371409 URAHP GAS8-AS1 CHMP1A SPATA2L TUBB3 GALNS LOC105371414 CDT1 CDH15 TUBB8P7 LOC339059 MVD DPEP1 SNAI3-AS1 LINC00304 LOC101927793 CTU2 GAS8 LOC100129697 MC1R DEF8 LOC107984817 PABPN1L TRAPPC2L LOC101927817 LOC105371419 MIR4722 SNORD68 ZNF276 SNAI3 CPNE7 SPIRE2 ANKRD11 SPG7 FAM157C SLC22A31 VPS9D1-AS1 CENPBD1 DBNDD1 IL17C RNF166 SPATA33 AFG3L1P PRDM7 LOC107987238 TCF25 LOC100287036
nsv509639	Chr.16:89513538 - 89775915 on Build GRCh38	Insertion	VPS9D1-AS1 FANCA CHMP1A SPATA33 SPATA2L RPL13 VPS9D1 CDK10 SNORD68 DPEP1 ZNF276 CPNE7 SPG7
nsv1931	Chr.16:89713649 - 89746701 on Build GRCh38	Insertion	VPS9D1-AS1 FANCA ZNF276 VPS9D1
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	VPS9D1-AS1 CENPBD1 DBNDD1 FANCA GAS8-AS1 CHMP1A MC1R SPATA33 DEF8 LOC107984817 SPATA2L TUBB3 VPS9D1 AFG3L1P CDK10 LOC105371419 DPEP1 ZNF276 TCF25 SPIRE2 GAS8
dgv873e212	Chr.16:89734780 - 89738373 on Build GRCh38	Loss	FANCA ZNF276
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	FANCA MC1R DEF8 LOC107984817 RPL13 LOC101927817 ZNF778 VPS9D1 CDK10 LOC105371419 SNORD68 ZNF276 CPNE7 SPIRE2 ANKRD11 SPG7 FAM157C VPS9D1-AS1 CENPBD1 DBNDD1 URAHP GAS8-AS1 CHMP1A SPATA33 SPATA2L TUBB3 LOC105371414 AFG3L1P TUBB8P7 DPEP1 PRDM7 TCF25 LOC100287036 GAS8
dgv875e212	Chr.16:89737043 - 89738817 on Build GRCh38	Loss	FANCA ZNF276
nsv833331	Chr.16:89726091 - 89849806 on Build GRCh38	Gain+Loss	LOC105371419 FANCA ZNF276 LOC107984817 SPIRE2
esv3572253	Chr.16:89737225 - 89738373 on Build GRCh38	Gain	FANCA ZNF276

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

DNA repair
protein complex assembly
male meiosis
male gonad development
female gonad development
interstrand cross-link repair
regulation of cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated

Function(s)

protein binding
DNA binding
zinc ion binding