Hs00055630_cn

• Gene Symbol: FANCA
• Assay Reference Genome Location: Chr.16:89737703 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 2175
• Gene Name: Fanconi anemia complementation group A
• Gene Aliases: FA, FA-H, FA1, FAA, FACA, FAH, FANCH
• Location: Chr.16:89737551-89816658 on Build GRCh38
• Assay Gene Location: Within Exon 44

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FANCA	NM_000135.2	43	5308	NP_000126.2
	NM_001286167.1	43	5312	NP_001273096.1
	X99226.1	43	5297	CAA67610.1

Target Gene Details

• Entrez Gene ID: 92822
• Gene Name: zinc finger protein 276
• Gene Aliases: CENP-Z, CENPZ, ZADT, ZFP276, ZNF477
• Location: Chr.16:89720368-89740925 on Build GRCh38
• Assay Gene Location: Overlaps Intron 12 - Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF276	NM_001113525.1			NP_001106997.1
	NM_152287.3			NP_689500.2
	NR_110122.1
	NR_110126.1
	NR_110128.1
	NR_110129.1
	XM_005256324.3			XP_005256381.1
	XM_005256328.3			XP_005256385.1
	XM_017023890.1			XP_016879379.1
	AK026482.1
	AK056405.1
	AK096762.1
	AK289801.1
	AK295770.1
	AK315793.1
	BC032781.1			AAH32781.2
	BC107603.1			AAI07604.1
	BC110348.1			AAI10349.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952079	Chr.16:89685593 - 89749492 on Build GRCh38	Deletion	VPS9D1-AS1 CDK10 SPATA2L VPS9D1 FANCA ZNF276
nsv457623	Chr.16:89664419 - 89853617 on Build GRCh38	Gain	LOC107984817 VPS9D1-AS1 CDK10 SPATA2L VPS9D1 FANCA ZNF276 LOC105371419 SPIRE2 SPATA33
dgv872e212	Chr.16:89731232 - 89738373 on Build GRCh38	Loss	FANCA ZNF276
nsv833330	Chr.16:89678466 - 89741783 on Build GRCh38	Loss	VPS9D1-AS1 CDK10 SPATA2L VPS9D1 FANCA ZNF276
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CYBA LINC00304 PABPN1L LOC107987238 SNAI3-AS1 VPS9D1-AS1 LOC100289580 CENPBD1 GALNS ACSF3 SPATA33 CDT1 SNORD68 CBFA2T3 LOC105371414 DBNDD1 MIR4722 FAM157C CDK10 LOC339059 TCF25 CDH15 RNF166 URAHP LOC105371419 SPIRE2 GAS8 LOC101927817 PRDM7 IL17C DEF8 SNAI3 DPEP1 FANCA ZNF778 MC1R CTU2 SLC22A31 MVD VPS9D1 CPNE7 PIEZO1 ZNF276 CHMP1A AFG3L1P LOC100129697 APRT LOC400558 LOC101927793 TUBB3 LOC107984817 GAS8-AS1 LOC105371409 SPATA2L RPL13 TUBB8P7 SPG7 LOC100287036 ANKRD11 TRAPPC2L
nsv509639	Chr.16:89513538 - 89775915 on Build GRCh38	Insertion	VPS9D1-AS1 CDK10 SPATA2L VPS9D1 CPNE7 ZNF276 SPATA33 RPL13 CHMP1A SPG7 SNORD68 DPEP1 FANCA
nsv1931	Chr.16:89713649 - 89746701 on Build GRCh38	Insertion	VPS9D1-AS1 VPS9D1 FANCA ZNF276
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	LOC107984817 DBNDD1 VPS9D1-AS1 GAS8-AS1 CDK10 SPATA2L TCF25 CENPBD1 VPS9D1 ZNF276 LOC105371419 SPIRE2 SPATA33 GAS8 CHMP1A AFG3L1P DEF8 DPEP1 FANCA MC1R TUBB3
dgv873e212	Chr.16:89734780 - 89738373 on Build GRCh38	Loss	FANCA ZNF276
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	VPS9D1-AS1 CENPBD1 VPS9D1 CPNE7 ZNF276 SPATA33 CHMP1A SNORD68 AFG3L1P LOC105371414 TUBB3 LOC107984817 DBNDD1 GAS8-AS1 FAM157C CDK10 SPATA2L TCF25 URAHP LOC105371419 SPIRE2 GAS8 RPL13 TUBB8P7 LOC101927817 SPG7 LOC100287036 PRDM7 DEF8 DPEP1 FANCA ANKRD11 ZNF778 MC1R
nsv833331	Chr.16:89726091 - 89849806 on Build GRCh38	Gain+Loss	LOC107984817 FANCA ZNF276 LOC105371419 SPIRE2
dgv874e212	Chr.16:89737043 - 89738373 on Build GRCh38	Loss	FANCA ZNF276
esv3572253	Chr.16:89737225 - 89738373 on Build GRCh38	Gain	FANCA ZNF276

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

DNA repair
protein complex assembly
male meiosis
male gonad development
female gonad development
interstrand cross-link repair
regulation of cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated

Function(s)

protein binding
DNA binding
zinc ion binding