Hs00140936_cn

• Gene Symbol: GNB5
• Assay Reference Genome Location: Chr.15:52122330 on build GRCh38
• Cytoband: 15q21.2

Target Gene Details

• Entrez Gene ID: 10681
• Gene Name: G protein subunit beta 5
• Gene Aliases: GB5
• Location: Chr.15:52120926-52191368 on Build GRCh38
• Assay Gene Location: Within Exon 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GNB5	NM_006578.3	11	1575	NP_006569.1
	NM_016194.3	13	1680	NP_057278.2
	XM_011521162.2	11	1932	XP_011519464.1
	XM_011521163.2	11	1457	XP_011519465.1
	XM_017021867.1	8	3198	XP_016877356.1
	AK094776.1	4	1303
	AK125702.1	8	2096
	AL117471.1	9	1287	CAB55946.1
	BC013997.2	11	1572	AAH13997.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471244	Chr.15:52013266 - 52219268 on Build GRCh38	Gain	MAPK6 LOC100129973 BCL2L10 MYO5C GNB5
nsv833005	Chr.15:52097672 - 52249133 on Build GRCh38	Gain	LOC100129973 BCL2L10 MYO5C GNB5

More Information

Additional Information:

For this assay, SNP(s) [rs79339279] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

protein folding
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of GTPase activity
negative regulation of voltage-gated calcium channel activity

Function(s)

GTPase activity
signal transducer activity
GTPase activator activity
protein binding
G-protein gamma-subunit binding
chaperone binding