Hs00157176_cn

• Gene Symbol: GZMA
• Assay Reference Genome Location: Chr.5:55110031 on build GRCh38
• Cytoband: 5q11.2

Target Gene Details

• Entrez Gene ID: 3001
• Gene Name: granzyme A
• Gene Aliases: CTLA3, HFSP
• Location: Chr.5:55102646-55110252 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GZMA	NM_006144.3			NP_006135.1
	BC015739.1			AAH15739.1
	CR456968.1			CAG33249.1
	M18737.1			AAA52647.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv4833	Chr.5:55082169 - 55126059 on Build GRCh38	Deletion	CDC20B GZMA
nsv830301	Chr.5:54930046 - 55127677 on Build GRCh38	Gain	LOC102467081 CDC20B GZMA ESM1 GZMK
nsv830302	Chr.5:55107550 - 55259351 on Build GRCh38	Gain	CCNO CDC20B GZMA DHX29 MIR449A MIR449B MCIDAS MIR449C GPX8

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease, serine protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

apoptotic process
immune response
cytolysis
negative regulation of endodeoxyribonuclease activity
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation of oxidoreductase activity
proteolysis involved in cellular protein catabolic process

Function(s)

serine-type endopeptidase activity
protein binding
protein homodimerization activity