Hs00187118_cn

• Gene Symbol: EXOC3
• Assay Reference Genome Location: Chr.5:453543 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11336
• Gene Name: exocyst complex component 3
• Gene Aliases: SEC6, SEC6L1, Sec6p
• Location: Chr.5:443184-471938 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOC3	NM_007277.4	4	666	NP_009208.2
	XM_011513948.2	4	701	XP_011512250.1
	XM_011513949.2	4	718	XP_011512251.1
	XM_011513950.2	3	596	XP_011512252.1
	XM_011513951.2	4	695	XP_011512253.1
	XM_017009000.1	4	701	XP_016864489.1
	XM_017009001.1	4	701	XP_016864490.1
	XM_017009002.1	4	701	XP_016864491.1
	XM_017009003.1	4	701	XP_016864492.1
	XM_017009004.1	5	779	XP_016864493.1
	XM_017009005.1	4	695	XP_016864494.1
	XM_017009006.1	4	695	XP_016864495.1
	AK074086.1	3	657	BAB84912.1
	AK131103.1	1	147	BAC85153.1
	AK315749.1	1	174
	AL545132.3	4	699
	AL832434.1	2	322	CAH10613.1
	BC001511.2	1	78	AAH01511.2
	BC019304.1	2	248	AAH19304.1
	BC064569.1	3	608	AAH64569.1
	GU727644.1	4	666

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759315	Chr.5:17263 - 595840 on Build GRCh38	Loss	SDHA HRAT5 LRRC14B PLEKHG4B LOC100288152 PDCD6 EXOC3 PP7080 SLC9A3 EXOC3-AS1 CCDC127 AHRR MIR4456
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	SDHA HRAT5 LRRC14B PLEKHG4B LOC100288152 PDCD6 TPPP EXOC3 PP7080 SLC9A3 ZDHHC11B CEP72 EXOC3-AS1 LOC101929895 ZDHHC11 CCDC127 AHRR MIR4456 LOC100996325
nsv830183	Chr.5:349237 - 502409 on Build GRCh38	Gain+Loss	LOC100288152 EXOC3 PP7080 SLC9A3 AHRR EXOC3-AS1
esv3603744	Chr.5:359572 - 478120 on Build GRCh38	Gain	LOC100288152 EXOC3 PP7080 SLC9A3 AHRR EXOC3-AS1
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	LOC100288152 TPPP EXOC3 PP7080 SLC9A3 ZDHHC11B CEP72 EXOC3-AS1 LOC101929895 ZDHHC11 AHRR MIR4456 LOC100996325
nsv461889	Chr.5:429874 - 598109 on Build GRCh38	Gain	LOC100288152 EXOC3 PP7080 SLC9A3 AHRR MIR4456 EXOC3-AS1
nsv1030767	Chr.5:154674 - 457840 on Build GRCh38	Gain	SDHA HRAT5 LRRC14B PLEKHG4B CCDC127 PDCD6 EXOC3 AHRR EXOC3-AS1
nsv1027279	Chr.5:337575 - 531110 on Build GRCh38	Gain	LOC100288152 EXOC3 PP7080 SLC9A3 AHRR EXOC3-AS1
nsv1019215	Chr.5:346521 - 661696 on Build GRCh38	Gain	LOC100288152 TPPP EXOC3 PP7080 SLC9A3 CEP72 AHRR MIR4456 EXOC3-AS1 LOC100996325
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	LOC101929895 LOC100288152 TPPP EXOC3 PP7080 SLC9A3 CEP72 AHRR MIR4456 EXOC3-AS1 LOC100996325
dgv9479n54	Chr.5:438449 - 567131 on Build GRCh38	Gain	LOC100288152 EXOC3 PP7080 SLC9A3 MIR4456 EXOC3-AS1
esv3603745	Chr.5:376684 - 458243 on Build GRCh38	Gain	EXOC3 AHRR EXOC3-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

exocytosis
protein transport
exocyst localization
cell-cell adhesion

Function(s)

SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion