Hs00214089_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37126676 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3	10	3207	NP_000869.1
	BC025691.1	10	3190	AAH25691.1
	M26062.1	10	3207	AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	TMPRSS6 LOC100506271 SSTR3 MPST MFNG LGALS1 IL2RB GGA1 TEX33 RAC2 LOC102724378 CARD10 TRIOBP PDXP ELFN2 CDC42EP1 SH3BP1 LGALS2 LOC101927051 CYTH4 TST NOL12 KCTD17 C1QTNF6
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	TMPRSS6 MPST IL2RB TEX33 TST KCTD17 LL22NC01-81G9.3
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	TMPRSS6 MPST IL2RB TEX33 TST KCTD17 C1QTNF6 LL22NC01-81G9.3
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	TMPRSS6 MPST IL2RB TEX33 TST KCTD17 LL22NC01-81G9.3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding