Hs00221484_cn

• Gene Symbol: NKIRAS1
• Assay Reference Genome Location: Chr.3:23917044 on build GRCh38
• Cytoband: 3p24.2

Target Gene Details

• Entrez Gene ID: 28512
• Gene Name: NFKB inhibitor interacting Ras like 1
• Gene Aliases: KBRAS1, kappaB-Ras1
• Location: Chr.3:23889536-23917046 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NKIRAS1	NM_020345.3			NP_065078.1
	XM_005265077.4			XP_005265134.1
	XM_005265078.3			XP_005265135.1
	AK027749.1			BAB55341.1
	BG713995.1

Target Gene Details

• Entrez Gene ID: 6138
• Gene Name: ribosomal protein L15
• Gene Aliases: DBA12, EC45, L15, RPL10, RPLY10, RPYL10
• Location: Chr.3:23916804-23923696 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RPL15	NM_001253379.1	1	241	NP_001240308.1
	NM_001253384.1	1	241	NP_001240313.1
	NM_002948.3	1	241	NP_002939.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1005186	Chr.3:21989661 - 24089392 on Build GRCh38	Gain	NR1D2 UBE2E2-AS1 UBE2E1-AS1 ZNF385D UBE2E1 UBE2E2 NKIRAS1 RPL15

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein, translational protein

Gene Ontology Categories:

Process(es)

I-kappaB kinase/NF-kappaB signaling
small GTPase mediated signal transduction
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
cytoplasmic translation
rRNA processing
translation
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
cell-cell adhesion

Function(s)

GTPase activity
GTP binding
RNA binding
structural constituent of ribosome
protein binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion