Hs00255518_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175457 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 11 - Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	CYSRT1 TMEM210 RNF224 SLC34A3 UAP1L1 DPP7 RNF208 ANAPC2 SSNA1 GRIN1 TPRN MAN1B1-AS1 MAN1B1 LOC101930307 NDOR1 MIR3621 TMEM203 LRRC26
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	CYSRT1 NELFB RNF224 SLC34A3 RNF208 ANAPC2 SSNA1 FAM166A TPRN TOR4A STPG3 C9orf173-AS1 NDOR1 EXD3 TUBB4B TMEM203 NRARP
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	MIR4292 SLC34A3 DPP7 ANAPC2 TRAF2 FBXW5 C9orf139 TOR4A NRARP LRRC26 PTGDS C9orf172 ENTPD2 TMEM210 NELFB CCDC183-AS1 RNF224 UAP1L1 LCN12 EDF1 MAN1B1-AS1 STPG3 MAN1B1 NDOR1 C8G CLIC3 LCNL1 PHPT1 ABCA2 PRR31 CYSRT1 MIR4479 CCDC183 C9orf142 MIR7114 FAM166A TPRN NPDC1 LOC101930307 C9orf173-AS1 TUBB4B SAPCD2 MAMDC4 ENTPD8 RABL6 RNF208 FUT7 NOXA1 SSNA1 GRIN1 PNPLA7 MIR3621 EXD3 TMEM203 NSMF
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	CYSRT1 TMEM210 NELFB RNF224 SLC34A3 RNF208 ANAPC2 SSNA1 FAM166A GRIN1 TPRN TOR4A STPG3 C9orf173-AS1 NDOR1 MIR3621 EXD3 TUBB4B TMEM203 NRARP LRRC26
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	CYSRT1 TMEM210 ENTPD8 NELFB RNF224 SLC34A3 RNF208 ANAPC2 NOXA1 SSNA1 FAM166A GRIN1 TPRN TOR4A STPG3 C9orf173-AS1 NDOR1 MIR3621 EXD3 TUBB4B TMEM203 NRARP LRRC26
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	TMEM210 UAP1L1 DPP7 FUT7 ANAPC2 SSNA1 GRIN1 MAN1B1-AS1 NPDC1 C9orf139 MAN1B1 LOC101930307 MIR3621 SAPCD2 LRRC26 ENTPD2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	MIR4292 SLC34A3 DPP7 ANAPC2 TRAF2 FAM69B FBXW5 MIR6722 SNORA17B C9orf139 TOR4A LINC01451 NRARP LRRC26 PTGDS C9orf172 ENTPD2 TMEM210 NELFB LCN8 CCDC183-AS1 RNF224 UAP1L1 LCN12 EDF1 MAN1B1-AS1 STPG3 MAN1B1 LCN10 AGPAT2 SNHG7 NDOR1 C8G HSPC324 SNORA17A CLIC3 LOC100128593 LCNL1 PHPT1 ABCA2 PRR31 CYSRT1 EGFL7 MIR4479 CCDC183 C9orf142 FAM166A TPRN NPDC1 LOC101930307 C9orf173-AS1 LCN6 TUBB4B SAPCD2 MAMDC4 RABL6 RNF208 FUT7 TMEM141 SSNA1 GRIN1 MIR126 MIR3621 EXD3 TMEM203 LCN15

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity