Hs00255518_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175457 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 11 - Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	TPRN TMEM203 UAP1L1 MIR3621 NDOR1 TMEM210 MAN1B1 CYSRT1 GRIN1 SLC34A3 LRRC26 MAN1B1-AS1 ANAPC2 RNF224 RNF208 SSNA1 DPP7 LOC101930307
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	EXD3 TPRN TMEM203 NDOR1 CYSRT1 NRARP SLC34A3 TOR4A ANAPC2 TUBB4B RNF224 STPG3 NELFB RNF208 C9orf173-AS1 SSNA1 FAM166A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	MIR4479 EXD3 UAP1L1 TMEM210 MIR7114 RABL6 MAN1B1 CLIC3 GRIN1 LRRC26 MAMDC4 MAN1B1-AS1 MIR4292 RNF224 NELFB SSNA1 DPP7 PHPT1 C9orf142 C8G SLC34A3 TRAF2 FBXW5 TOR4A LCNL1 C9orf172 ANAPC2 CCDC183 ENTPD2 LOC101930307 MIR3621 LCN12 PTGDS FUT7 PRR31 NSMF EDF1 RNF208 C9orf173-AS1 FAM166A ABCA2 TPRN TMEM203 ENTPD8 NDOR1 C9orf139 CYSRT1 NOXA1 NRARP CCDC183-AS1 NPDC1 SAPCD2 TUBB4B PNPLA7 STPG3
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	EXD3 TPRN TMEM203 MIR3621 NDOR1 TMEM210 CYSRT1 GRIN1 NRARP SLC34A3 LRRC26 TOR4A ANAPC2 TUBB4B RNF224 STPG3 NELFB RNF208 C9orf173-AS1 SSNA1 FAM166A
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	UAP1L1 MIR3621 C9orf139 TMEM210 MAN1B1 GRIN1 FUT7 LRRC26 MAN1B1-AS1 NPDC1 ANAPC2 SAPCD2 ENTPD2 SSNA1 DPP7 LOC101930307
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	EXD3 TPRN TMEM203 MIR3621 ENTPD8 NDOR1 TMEM210 CYSRT1 NOXA1 GRIN1 NRARP SLC34A3 LRRC26 TOR4A ANAPC2 TUBB4B RNF224 STPG3 NELFB RNF208 C9orf173-AS1 SSNA1 FAM166A
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	MIR4479 EXD3 UAP1L1 TMEM210 RABL6 MAN1B1 CLIC3 GRIN1 LRRC26 MAMDC4 MAN1B1-AS1 MIR4292 RNF224 SNORA17B NELFB HSPC324 SSNA1 DPP7 LCN10 PHPT1 FAM69B EGFL7 C9orf142 LCN8 C8G LINC01451 SLC34A3 TRAF2 LOC100128593 SNHG7 FBXW5 TOR4A LCNL1 C9orf172 ANAPC2 CCDC183 ENTPD2 LOC101930307 MIR3621 LCN12 PTGDS FUT7 MIR6722 PRR31 EDF1 LCN15 SNORA17A RNF208 C9orf173-AS1 FAM166A ABCA2 TPRN TMEM203 NDOR1 C9orf139 CYSRT1 TMEM141 AGPAT2 NRARP LCN6 CCDC183-AS1 NPDC1 MIR126 SAPCD2 TUBB4B STPG3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity