Hs00262314_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20113240 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1			NP_001244923.1
	NM_022727.5			NP_073564.3
	NM_182984.4			NP_892029.2
	XM_011530139.2			XP_011528441.1
	XM_011530141.1			XP_011528443.1
	XM_011530142.2			XP_011528444.1
	XM_017028770.1			XP_016884259.1
	AK025106.1			BAB15067.1
	AK057029.1			BAB71349.1
	BC013352.2			AAH13352.2
	BC017184.2			AAH17184.2
	BC108251.1			AAI08252.1
	CR456354.1			CAG30240.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	LOC440792 LINC00896 DGCR8 CCDC188 LOC284865 DGCR6L TRMT2A MIR1286 MIR6816 MIR1306 RANBP1 MIR3618 RTN4R ZDHHC8
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	LOC440792 CLDN5 LOC101927859 DGCR8 CCDC188 MIR185 C22orf29 COMT LOC284865 GP1BB TBX1 TRMT2A MIR1286 MIR4761 MIR3618 SEPT5 RTN4R ZDHHC8 UFD1L LINC00896 SEPT5-GP1BB DGCR6L TANGO2 MIR6816 GNB1L ARVCF TXNRD2 MIR1306 RANBP1 CDC45 LINC00895
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	MIR6816 ARVCF DGCR8 MIR1306 RANBP1 MIR185 MIR3618 ZDHHC8 TANGO2 TRMT2A
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	LOC440792 DGCR8 CCDC188 MIR185 C22orf29 COMT LOC284865 GP1BB TBX1 TRMT2A MIR1286 MIR4761 MIR3618 SEPT5 RTN4R ZDHHC8 LINC00896 SEPT5-GP1BB DGCR6L TANGO2 MIR6816 GNB1L ARVCF TXNRD2 MIR1306 RANBP1
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	LOC440792 DGCR8 CCDC188 MIR185 C22orf29 COMT LOC284865 GP1BB TBX1 TRMT2A MIR1286 MIR4761 MIR3618 SEPT5 RTN4R ZDHHC8 LINC00896 SEPT5-GP1BB DGCR6L TANGO2 MIR6816 GNB1L ARVCF TXNRD2 MIR1306 RANBP1
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	LOC440792 LINC00896 DGCR8 CCDC188 LOC284865 DGCR6L TANGO2 TRMT2A MIR1286 MIR6816 MIR1306 RANBP1 MIR3618 RTN4R ZDHHC8
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	MIR1286 LINC00896 MIR6816 DGCR8 CCDC188 MIR1306 RANBP1 MIR3618 LOC284865 RTN4R ZDHHC8 TRMT2A
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	LOC440792 LINC00896 DGCR8 CCDC188 MIR185 LOC284865 DGCR6L TANGO2 TRMT2A MIR1286 MIR6816 MIR1306 RANBP1 MIR3618 RTN4R ZDHHC8
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	LOC440792 LINC00896 DGCR8 CCDC188 MIR185 C22orf29 COMT LOC284865 DGCR6L TBX1 TANGO2 TRMT2A MIR1286 MIR6816 GNB1L ARVCF MIR4761 TXNRD2 MIR1306 RANBP1 MIR3618 RTN4R ZDHHC8
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	MIR6816 DGCR8 CCDC188 MIR1306 RANBP1 MIR185 MIR3618 ZDHHC8 TANGO2 TRMT2A
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	LOC440792 LINC00896 DGCR8 CCDC188 LOC284865 TRMT2A MIR1286 MIR6816 MIR1306 RANBP1 MIR3618 RTN4R ZDHHC8

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding