Hs00281974_cn

• Gene Symbol: POLN
• Assay Reference Genome Location: Chr.4:2081685 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 353497
• Gene Name: DNA polymerase nu
• Gene Aliases: POL4P
• Location: Chr.4:2071958-2242164 on Build GRCh38
• Assay Gene Location: Within Exon 22

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLN	NM_181808.3	22	2653	NP_861524.2
	AF044578.1	15	1157	AAD02338.1
	AK131239.1	13	1263	BAD18421.1
	AY136549.1	20	2256	AAN52116.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2726835	Chr.4:2019561 - 2959568 on Build GRCh38	Deletion	CFAP99 MFSD10 FAM193A HAUS3 NOP14 C4orf48 RNF4 MIR4800 NOP14-AS1 TNIP2 POLN SH3BP2 ADD1 MXD4 ZFYVE28 NAT8L
nsv949757	Chr.4:2056974 - 2082173 on Build GRCh38	Deletion	POLN NAT8L

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed DNA polymerase

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
DNA-dependent DNA replication
translesion synthesis
interstrand cross-link repair
nucleic acid phosphodiester bond hydrolysis

Function(s)

DNA binding
DNA-directed DNA polymerase activity
protein binding
5'-3' exonuclease activity
cyclin binding