Hs00309743_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76330076 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3	2	462	NP_036611.2
	AB024334.1	2	414	BAA85184.1
	AF142498.1	2	245	AAD48408.1
	AK024230.1	2	426
	AK293505.1
	AK295029.1	3	341
	BC020963.2	2	436	AAH20963.1
	CR541904.1	2	245	CAG46702.1
	CR541925.1	2	245	CAG46723.1
	DC343104.1	2	490

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	LOC100133091 FDPSP2 SRRM3 DTX2 DTX2P1-UPK3BP1-PMS2P11 HSPB1 POMZP3 SSC4D LOC105375355 SPDYE16 ZP3 YWHAG
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	LOC100133091 DTX2 DTX2P1-UPK3BP1-PMS2P11 SPDYE17 SSC4D ZP3 PMS2P9 FDPSP2 POMZP3 FGL2 SPDYE18 CCDC146 LOC105375355 SPDYE16 YWHAG
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	LOC100133091 DTX2 RHBDD2 NSUN5P1 POM121C NCF1C SNORA14A ZP3 PMS2P10 GTF2IP1 TMEM120A FDPSP2 STYXL1 LOC107986711 LOC105375355 SPDYE16 SRRM3 HSPB1 MIR4651 SSC4D GTF2IRD2B CCL26 STAG3L1 TRIM73 CCL24 PMS2P3 POMZP3 PMS2P2 LOC541473 LOC441259 MDH2 HIP1 GTF2IP7 POR SPDYE5 YWHAG
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	LOC100133091 DTX2 RHBDD2 POM121C SNORA14A ZP3 TMEM120A FDPSP2 STYXL1 LOC107986711 LOC105375355 SPDYE16 SRRM3 HSPB1 MIR4651 SSC4D CCL26 CCL24 PMS2P3 POMZP3 MDH2 HIP1 GTF2IP7 POR SPDYE5 YWHAG

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding