Hs00329924_cn

• Gene Symbol: APEX2
• Assay Reference Genome Location: Chr.X:55007571 on build GRCh38
• Cytoband: Xp11.21

Target Gene Details

• Entrez Gene ID: 27301
• Gene Name: apurinic/apyrimidinic endodeoxyribonuclease 2
• Gene Aliases: APE2, APEXL2, XTH2, ZGRF2
• Location: Chr.X:55000323-55007873 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APEX2	NM_001271748.1	5	1612	NP_001258677.1
	NM_014481.3	6	1793	NP_055296.2
	AB021260.1	6	1753	BAA78422.1
	AB049211.1	6	1716	BAB13764.1
	AF119046.1	6	1759	AAD43041.1
	AJ011311.1	6	1759	CAB45242.1
	AK301555.1	5	1567
	BC002959.1	6	1731	AAH02959.1
	BM795632.1	1	155

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2740175	Chr.X:52862926 - 55652533 on Build GRCh38	Deletion	FAM120C GPR173 MIR98 GNL3L PAGE5 MAGEH1 MTRNR2L10 WNK3 ALAS2 FOXR2 MIR4536-1 SMC1A TSPYL2 ITIH6 MIR6857 USP51 MIRLET7F2 PFKFB1 PHF8 IQSEC2 TSR2 XAGE3 FAM156B LOC100421746 PAGE2B TRO PAGE2 KDM5C RIBC1 HUWE1 FAM156A APEX2 FAM104B MAGED2 MIR4536-2 MIR6894 SNORA109 KANTR FGD1 SNORA11 HSD17B10 MIR6895 PAGE3
nsv435891	Chr.X:52861979 - 55653313 on Build GRCh38	Deletion	FAM120C GPR173 MIR98 GNL3L PAGE5 MAGEH1 MTRNR2L10 WNK3 ALAS2 FOXR2 MIR4536-1 SMC1A TSPYL2 ITIH6 MIR6857 USP51 MIRLET7F2 PFKFB1 PHF8 IQSEC2 TSR2 XAGE3 FAM156B LOC100421746 PAGE2B TRO PAGE2 KDM5C RIBC1 HUWE1 FAM156A APEX2 FAM104B MAGED2 MIR4536-2 MIR6894 SNORA109 KANTR FGD1 SNORA11 HSD17B10 MIR6895 PAGE3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

base-excision repair
DNA recombination
cell cycle
nucleic acid phosphodiester bond hydrolysis

Function(s)

DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
zinc ion binding
double-stranded DNA 3'-5' exodeoxyribonuclease activity