Hs00350824_cn

• Gene Symbol: GSG2
• Assay Reference Genome Location: Chr.17:3726444 on build GRCh38
• Cytoband: 17p13.2

Target Gene Details

• Entrez Gene ID: 83903
• Gene Name: germ cell associated 2, haspin
• Gene Aliases: HASPIN
• Location: Chr.17:3723903-3726699 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GSG2	NM_031965.2	1	2542	NP_114171.2
	AB039834.3	1	2539
	AF289865.1	1	2538	AAK30300.1
	AK056691.1	2	1428	BAB71255.1
	AK292715.1	1	2528
	AK310546.1
	BC047457.1	1	2523	AAH47457.1

Target Gene Details

• Entrez Gene ID: 3682
• Gene Name: integrin subunit alpha E
• Gene Aliases: CD103, HUMINAE
• Location: Chr.17:3714625-3803766 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ITGAE	NM_002208.4			NP_002199.3
	XM_011523823.2			XP_011522125.1
	XM_011523825.2			XP_011522127.1
	XM_011523827.2			XP_011522129.1
	XM_011523828.2			XP_011522130.1
	XM_017024586.1			XP_016880075.1
	BC113436.1
	BC117207.1
	L25851.2			AAB59359.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1065489	Chr.17:2631416 - 3948349 on Build GRCh38	Gain	OR3A2 OR3A1 TRPV1 CTNS CAMKK1 RAP1GAP2 P2RX1 ITGAE MIR6776 ASPA OR1E1 OR1G1 LOC101927911 PAFAH1B1 OR1D2 MIR1253 EMC6 CLUH ATP2A3 SPATA22 OR1D4 OR1A2 OR3A4P OR1E2 P2RX5-TAX1BP3 GSG2 LOC105371591 LOC105371592 TAX1BP3 TRPV3 OR3A3 SHPK CCDC92B NCBP3 OR1A1 P2RX5 OR1D5
nsv574237	Chr.17:3486822 - 3729542 on Build GRCh38	Loss	TRPV1 GSG2 CTNS TAX1BP3 TRPV3 SHPK ITGAE SPATA22 ASPA P2RX5 EMC6 P2RX5-TAX1BP3
nsv469791	Chr.17:3700760 - 3885899 on Build GRCh38	Loss	GSG2 CAMKK1 NCBP3 ITGAE
nsv1055740	Chr.17:3381841 - 3890153 on Build GRCh38	Gain	OR3A2 TRPV1 CTNS CAMKK1 ITGAE SPATA22 ASPA OR1E2 P2RX5-TAX1BP3 OR1E1 GSG2 TAX1BP3 TRPV3 OR3A3 SHPK NCBP3 P2RX5 EMC6
nsv833342	Chr.17:3626188 - 3806082 on Build GRCh38	Loss	GSG2 CTNS TAX1BP3 SHPK ITGAE P2RX5 EMC6 P2RX5-TAX1BP3

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

protein phosphorylation
mitotic sister chromatid cohesion
intracellular signal transduction
protein localization to chromosome, centromeric region
regulation of spindle checkpoint
histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore
cell adhesion
integrin-mediated signaling pathway
extracellular matrix organization

Function(s)

protein kinase activity
protein binding
ATP binding
histone kinase activity (H3-T3 specific)
metal ion binding