Hs00380287_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20112308 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1	12	2544	NP_001244923.1
	NM_022727.5	12	2522	NP_073564.3
	NM_182984.4	13	2398	NP_892029.2
	XM_011530139.2	13	2383	XP_011528441.1
	XM_011530141.1	11	1758	XP_011528443.1
	XM_011530142.2	9	1416	XP_011528444.1
	XM_017028770.1	12	2586	XP_016884259.1
	AI539558.1
	AK025106.1			BAB15067.1
	AK057029.1			BAB71349.1
	BC013352.2			AAH13352.2
	BC017184.2	13	2284	AAH17184.2
	BC108251.1			AAI08252.1
	BX349507.2	1	405
	CA440188.1	1	460

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	LOC284865 MIR1306 MIR1286 RANBP1 DGCR8 RTN4R MIR6816 ZDHHC8 CCDC188 LOC440792 DGCR6L LINC00896 TRMT2A MIR3618
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	C22orf29 LOC284865 ARVCF MIR185 TXNRD2 MIR1286 RANBP1 RTN4R LOC101927859 COMT GNB1L SEPT5 LINC00896 TRMT2A SEPT5-GP1BB CLDN5 MIR1306 CDC45 DGCR8 MIR6816 ZDHHC8 CCDC188 TBX1 UFD1L LOC440792 DGCR6L LINC00895 MIR4761 TANGO2 GP1BB MIR3618
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	ARVCF MIR185 MIR1306 TRMT2A RANBP1 DGCR8 MIR6816 TANGO2 ZDHHC8 MIR3618
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	C22orf29 LOC284865 ARVCF MIR185 TXNRD2 MIR1286 RANBP1 RTN4R COMT GNB1L SEPT5 LINC00896 TRMT2A SEPT5-GP1BB MIR1306 DGCR8 MIR6816 ZDHHC8 CCDC188 TBX1 LOC440792 DGCR6L MIR4761 TANGO2 GP1BB MIR3618
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	C22orf29 LOC284865 ARVCF MIR185 TXNRD2 MIR1286 RANBP1 RTN4R COMT GNB1L SEPT5 LINC00896 TRMT2A SEPT5-GP1BB MIR1306 DGCR8 MIR6816 ZDHHC8 CCDC188 TBX1 LOC440792 DGCR6L MIR4761 TANGO2 GP1BB MIR3618
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	LOC284865 MIR1306 MIR1286 RANBP1 DGCR8 RTN4R MIR6816 ZDHHC8 CCDC188 LOC440792 DGCR6L LINC00896 TRMT2A TANGO2 MIR3618
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	LOC284865 LINC00896 MIR1306 TRMT2A MIR1286 RANBP1 DGCR8 RTN4R MIR6816 ZDHHC8 CCDC188 MIR3618
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	LOC284865 MIR185 MIR1306 MIR1286 RANBP1 DGCR8 RTN4R MIR6816 ZDHHC8 CCDC188 LOC440792 DGCR6L LINC00896 TRMT2A TANGO2 MIR3618
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	C22orf29 LOC284865 ARVCF MIR185 MIR1306 TXNRD2 MIR1286 RANBP1 DGCR8 RTN4R MIR6816 ZDHHC8 CCDC188 COMT TBX1 GNB1L LOC440792 DGCR6L LINC00896 MIR4761 TRMT2A TANGO2 MIR3618
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	MIR185 MIR1306 TRMT2A RANBP1 DGCR8 MIR6816 TANGO2 ZDHHC8 CCDC188 MIR3618
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	LOC284865 MIR1306 MIR1286 RANBP1 DGCR8 RTN4R MIR6816 ZDHHC8 CCDC188 LOC440792 LINC00896 TRMT2A MIR3618

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding