Hs00446034_cn

• Gene Symbol: POLR1C
• Assay Reference Genome Location: Chr.6:43517359 on build GRCh38
• Cytoband: 6p21.1

Target Gene Details

• Entrez Gene ID: 9533
• Gene Name: RNA polymerase I subunit C
• Gene Aliases: AC40, HLD11, RPA39, RPA40, RPA5, RPAC1, RPC40, TCS3
• Location: Chr.6:43517024-43562404 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR1C	NM_001318876.1			NP_001305805.1
	NM_203290.3			NP_976035.1
	XM_011515000.2			XP_011513302.1
	AF008442.1			AAC14354.1
	AF047441.1			AAC39892.1
	AK293561.1
	BC008118.1			AAH08118.1
	BC008863.2			AAH08863.1
	BM828768.1
	DW415914.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv603000	Chr.6:43397622 - 43524840 on Build GRCh38	Loss	MIR6780B TJAP1 POLR1C YIPF3 LRRC73 ABCC10 DLK2 XPO5
nsv818414	Chr.6:43507736 - 43528924 on Build GRCh38	Gain	POLR1C YIPF3 LRRC73 XPO5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase I promoter
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of gene expression, epigenetic

Function(s)

RNA polymerase I activity
RNA polymerase III activity
DNA binding
DNA-directed RNA polymerase activity
protein binding
protein dimerization activity