Hs00463758_cn

• Gene Symbol: TKFC
• Assay Reference Genome Location: Chr.11:61341907 on build GRCh38
• Cytoband: 11q12.2

Target Gene Details

• Entrez Gene ID: 26007
• Gene Name: triokinase and FMN cyclase
• Gene Aliases: DAK, NET45
• Location: Chr.11:61333182-61353426 on Build GRCh38
• Assay Gene Location: Overlaps Exon 9 - Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TKFC	NM_015533.3			NP_056348.2
	XM_011544912.2			XP_011543214.1
	XM_017017517.1			XP_016873006.1
	XM_017017518.1			XP_016873007.1
	XM_017017519.1			XP_016873008.1
	XM_017017520.1			XP_016873009.1
	XM_017017521.1			XP_016873010.1
	XM_017017522.1			XP_016873011.1
	XM_017017523.1			XP_016873012.1
	XM_017017524.1			XP_016873013.1
	AK023915.1			BAB14722.1
	AK223580.1			BAD97300.1
	AK308553.1
	BC001341.1			AAH01341.1
	BC120929.1
	DQ138290.1			ABA10576.1
	DQ344550.1			ABC70184.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428259	Chr.11:61049513 - 61356164 on Build GRCh38	Gain+Loss	VWCE PGA4 PGA5 VPS37C CD5 CYB561A3 DDB1 TKFC LOC105369325 PGA3
nsv832177	Chr.11:61185118 - 61356164 on Build GRCh38	Loss	VWCE PGA4 PGA5 CYB561A3 DDB1 TKFC PGA3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cyclase

Gene Ontology Categories:

Process(es)

glycerol metabolic process
negative regulation of MDA-5 signaling pathway
cellular carbohydrate metabolic process
innate immune response
regulation of innate immune response
carbohydrate phosphorylation
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

Function(s)

glycerone kinase activity
protein binding
ATP binding
FAD-AMP lyase (cyclizing) activity
metal ion binding
triokinase activity