Hs00495620_cn

• Gene Symbol: GGT5
• Assay Reference Genome Location: Chr.22:24219963 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 2687
• Gene Name: gamma-glutamyltransferase 5
• Gene Aliases: GGL, GGT 5, GGT-REL, GGTLA1
• Location: Chr.22:24219654-24245142 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GGT5	NM_001099781.2	12	2188	NP_001093251.1
	NM_001099782.2	11	2089	NP_001093252.1
	NM_001302464.1	12	2181	NP_001289393.1
	NM_001302465.1	10	1957	NP_001289394.1
	NM_004121.3	12	2185	NP_004112.2
	XM_005261557.2	13	2217	XP_005261614.1
	XM_005261558.2	13	2214	XP_005261615.1
	XM_011530133.1	13	2232	XP_011528435.1
	XM_011530134.1	12	2139	XP_011528436.1
	XM_011530135.1	12	2136	XP_011528437.1
	XM_011530136.1	13	2231	XP_011528438.1
	XM_011530137.2	12	2206	XP_011528439.1
	XM_017028768.1	12	2118	XP_016884257.1
	XM_017028769.1	11	2043	XP_016884258.1
	AI581436.1	1	313
	AK225661.1	11	2025
	AK226019.1	11	2025
	AK292006.1	12	1967
	AK293683.1	10	1897
	AK297869.1	13	1960
	AK312401.1
	AL117414.1	12	2121	CAB55910.1
	BC011362.1	12	2174	AAH11362.1
	BC073999.1	12	2105	AAH73999.1
	BT009808.1			AAP88810.1
	BU728951.1
	CT841518.1	12	1926	CAJ86448.1
	M64099.1	12	2109	AAA58503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L GSTT2 ADORA2A GUCD1 CABIN1 GSTTP1 SLC2A11 MIF-AS1 RGL4 ZDHHC8P1 GSTT2B LOC100652871 LRRC75B DERL3 ADORA2A-AS1 MMP11 DRICH1 CES5AP1 DDT SNRPD3 SUSD2 C22orf15 VPREB3 PCAT14 POM121L9P UPB1 DDTL LOC388882 LOC107985559 SMARCB1 ZNF70 IGLL1 GGT1 MIF CHCHD10 GUSBP11 LOC101929374 LOC107985555
nsv483072	Chr.22:24074769 - 24269273 on Build GRCh38	Loss	GGT5 SUSD2 CABIN1 POM121L9P
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L SNRPD3 SUSD2 ADORA2A GUCD1 CABIN1 POM121L9P UPB1 GSTTP1 GGT1 LRRC75B BCRP3 ADORA2A-AS1
esv3647429	Chr.22:24218290 - 24220976 on Build GRCh38	Loss	GGT5
nsv834157	Chr.22:24057654 - 24242235 on Build GRCh38	Gain	GGT5 SUSD2 CABIN1
nsv528842	Chr.22:24139262 - 24247641 on Build GRCh38	Loss	GGT5 SUSD2 CABIN1
nsv834158	Chr.22:24126288 - 24293870 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L SUSD2 CABIN1 POM121L9P
nsv528009	Chr.22:24219538 - 24247641 on Build GRCh38	Loss	GGT5
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	SPECC1L-ADORA2A GGT5 SPECC1L GSTT2 ADORA2A GUCD1 CABIN1 GSTTP1 BCR SLC2A11 MIF-AS1 RGL4 ZDHHC8P1 GSTT2B LOC100652871 LRRC75B DERL3 ADORA2A-AS1 MMP11 DRICH1 CES5AP1 DDT SNRPD3 SUSD2 C22orf15 POM121L10P VPREB3 PCAT14 POM121L9P UPB1 DDTL LOC388882 LOC107985559 SMARCB1 ZNF70 IGLL1 GGT1 MIF CHCHD10 GUSBP11 BCRP3 LOC101929374 LOC107985555
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L GSTT2 ADORA2A GUCD1 CABIN1 GSTTP1 SLC2A11 MIF-AS1 RGL4 ZDHHC8P1 GSTT2B LOC100652871 LRRC75B DERL3 ADORA2A-AS1 MMP11 DRICH1 CES5AP1 DDT SNRPD3 SUSD2 C22orf15 VPREB3 PCAT14 POM121L9P UPB1 DDTL LOC388882 LOC107985559 SMARCB1 ZNF70 IGLL1 GGT1 MIF CHCHD10 GUSBP11 LOC101929374 LOC107985555
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L SNRPD3 SUSD2 ADORA2A GUCD1 CABIN1 POM121L9P UPB1 GGT1 LRRC75B ADORA2A-AS1
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L GSTT2 ADORA2A GUCD1 CABIN1 GSTTP1 SLC2A11 MIF-AS1 RGL4 ZDHHC8P1 GSTT2B LOC100652871 LRRC75B DERL3 ADORA2A-AS1 MMP11 DRICH1 CES5AP1 DDT SNRPD3 SUSD2 C22orf15 POM121L10P VPREB3 PCAT14 POM121L9P UPB1 DDTL LOC388882 LOC107985559 SMARCB1 ZNF70 IGLL1 GGT1 MIF CHCHD10 GUSBP11 BCRP3 LOC101929374 LOC107985555
nsv953059	Chr.22:24214433 - 24259032 on Build GRCh38	Deletion	GGT5 POM121L9P
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	SPECC1L-ADORA2A GGT5 SPECC1L GSTT2 ADORA2A GUCD1 CABIN1 GSTTP1 SLC2A11 MIF-AS1 RGL4 ZDHHC8P1 GSTT2B LOC100652871 LRRC75B DERL3 ADORA2A-AS1 MMP11 DRICH1 CES5AP1 DDT SNRPD3 SUSD2 C22orf15 POM121L10P VPREB3 PCAT14 POM121L9P UPB1 DDTL LOC388882 LOC107985559 SMARCB1 ZNF70 IGLL1 GGT1 MIF CHCHD10 GUSBP11 BCRP3 LOC101929374 LOC107985555

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
cellular amino acid metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione biosynthetic process
inflammatory response
leukotriene biosynthetic process

Function(s)

gamma-glutamyltransferase activity
glutathione hydrolase activity