Hs00573357_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:683075 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2	5	2194	NP_005851.1
	AL050194.1	1	70
	AY358917.1	5	2175	AAQ89276.1
	BC005839.2	5	2180	AAH05839.1
	BQ319646.1
	U76702.1	5	2166	AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	ARID3A MIR4745 AZU1 PRTN3 PTBP1 RNF126 PRSS57 HCN2 MISP FSTL3 MED16 PALM LOC101928450 FGF22 POLRMT KISS1R RNU6-9 PLPPR3 MIR3187 R3HDM4 ELANE CFD
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	C2CD4C TPGS1 MIER2 BSG RNF126 PRSS57 THEG SHC2 MADCAM1 HCN2 FSTL3 GZMM FGF22 PLPP2 POLRMT ODF3L2 CDC34 LOC101929060
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	C2CD4C TPGS1 MIER2 BSG RNF126 PRSS57 THEG SHC2 MADCAM1 HCN2 MISP FSTL3 PALM LOC101928450 GZMM FGF22 POLRMT ODF3L2 CDC34 LOC101929060
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	C2CD4C TPGS1 ARID3A GRIN3B MIR4745 AZU1 PRTN3 PTBP1 RNF126 CNN2 THEG SHC2 FSTL3 MED16 PALM LOC101928450 GZMM FGF22 ODF3L2 RNU6-2 PLPPR3 TMEM259 POLR2E CFD ARHGAP45 BSG PRSS57 MADCAM1 HCN2 MISP LOC105372235 POLRMT GPX4 WDR18 ABCA7 CDC34 KISS1R RNU6-9 MIR3187 R3HDM4 ELANE
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	C2CD4C TPGS1 ARID3A GRIN3B MIR4745 AZU1 PRTN3 PTBP1 RNF126 SHC2 FSTL3 MED16 PALM LOC101928450 GZMM FGF22 ODF3L2 PLPPR3 CFD BSG PRSS57 MADCAM1 HCN2 MISP LOC105372235 POLRMT WDR18 CDC34 KISS1R RNU6-9 MIR3187 R3HDM4 ELANE

More Information

Additional Information:

For this assay, SNP(s) [rs80087121] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding