Hs00598394_cn

• Gene Symbol: DDX58
• Assay Reference Genome Location: Chr.9:32456399 on build GRCh38
• Cytoband: 9p21.1

Target Gene Details

• Entrez Gene ID: 23586
• Gene Name: DEXD/H-box helicase 58
• Gene Aliases: RIG-I, RIGI, RLR-1, SGMRT2
• Location: Chr.9:32455302-32526324 on Build GRCh38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DDX58	NM_014314.3	18	3659	NP_055129.2
	AK023661.1	11	2334
	AL137608.1	8	1920	CAB70840.1
	BC132786.1	18	3607
	BC136610.1	18	3607

More Information

• Set Membership: Intragenic, Exonic, non-DGV Variation

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
detection of virus
response to virus
positive regulation of gene expression
regulation of cell migration
negative regulation of type I interferon production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
regulation of type III interferon production
cytoplasmic pattern recognition receptor signaling pathway in response to virus
RIG-I signaling pathway
positive regulation of transcription factor import into nucleus
response to exogenous dsRNA
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity

Function(s)

double-stranded DNA binding
double-stranded RNA binding
single-stranded RNA binding
helicase activity
protein binding
ATP binding
zinc ion binding
identical protein binding