Hs00601901_cn

• Gene Symbol: EXOC3
• Assay Reference Genome Location: Chr.5:447729 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11336
• Gene Name: exocyst complex component 3
• Gene Aliases: SEC6, SEC6L1, Sec6p
• Location: Chr.5:443184-471938 on Build GRCh38
• Assay Gene Location: Overlaps Exon 4 - Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOC3	NM_007277.4			NP_009208.2
	XM_011513948.2			XP_011512250.1
	XM_011513949.2			XP_011512251.1
	XM_011513950.2			XP_011512252.1
	XM_011513951.2			XP_011512253.1
	XM_017009000.1			XP_016864489.1
	XM_017009001.1			XP_016864490.1
	XM_017009002.1			XP_016864491.1
	XM_017009003.1			XP_016864492.1
	XM_017009004.1			XP_016864493.1
	XM_017009005.1			XP_016864494.1
	XM_017009006.1			XP_016864495.1
	AK074086.1			BAB84912.1
	AL545132.3
	AL832434.1			CAH10613.1
	BC019304.1			AAH19304.1
	BC064569.1			AAH64569.1
	GU727644.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	LOC100288152 CCDC127 AHRR EXOC3 LOC101929895 PLEKHG4B PP7080 ZDHHC11 PDCD6 EXOC3-AS1 MIR4456 SLC9A3 LOC100996325 HRAT5 SDHA LRRC14B CEP72 ZDHHC11B TPPP
nsv830183	Chr.5:349237 - 502409 on Build GRCh38	Gain+Loss	LOC100288152 AHRR EXOC3 PP7080 EXOC3-AS1 SLC9A3
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	LOC100288152 AHRR EXOC3 LOC101929895 PP7080 ZDHHC11 EXOC3-AS1 MIR4456 SLC9A3 LOC100996325 CEP72 ZDHHC11B TPPP
nsv596626	Chr.5:429874 - 598109 on Build GRCh38	Gain	LOC100288152 AHRR EXOC3 PP7080 EXOC3-AS1 MIR4456 SLC9A3
nsv1030767	Chr.5:154674 - 457840 on Build GRCh38	Gain	HRAT5 CCDC127 AHRR SDHA EXOC3 LRRC14B PLEKHG4B PDCD6 EXOC3-AS1
nsv461890	Chr.5:438449 - 539195 on Build GRCh38	Gain	LOC100288152 EXOC3 PP7080 EXOC3-AS1 MIR4456 SLC9A3
esv2759315	Chr.5:17263 - 595840 on Build GRCh38	Loss	LOC100288152 CCDC127 AHRR EXOC3 PLEKHG4B PP7080 PDCD6 EXOC3-AS1 MIR4456 SLC9A3 HRAT5 SDHA LRRC14B
nsv1032824	Chr.5:335214 - 449516 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1
esv3603744	Chr.5:359572 - 478120 on Build GRCh38	Gain	LOC100288152 AHRR EXOC3 PP7080 EXOC3-AS1 SLC9A3
nsv4673	Chr.5:414170 - 449449 on Build GRCh38	Insertion	AHRR EXOC3 EXOC3-AS1
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	LOC100996325 LOC100288152 AHRR EXOC3 LOC101929895 CEP72 PP7080 TPPP EXOC3-AS1 MIR4456 SLC9A3
nsv1019215	Chr.5:346521 - 661696 on Build GRCh38	Gain	LOC100996325 LOC100288152 AHRR EXOC3 CEP72 PP7080 TPPP EXOC3-AS1 MIR4456 SLC9A3
nsv1027279	Chr.5:337575 - 531110 on Build GRCh38	Gain	LOC100288152 AHRR EXOC3 PP7080 EXOC3-AS1 SLC9A3
nsv830184	Chr.5:378153 - 451752 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1
esv3603745	Chr.5:376684 - 458243 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

exocytosis
protein transport
exocyst localization
cell-cell adhesion

Function(s)

SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion