Hs00611946_cn

• Gene Symbol: MPPE1
• Assay Reference Genome Location: Chr.18:11886522 on build GRCh38
• Cytoband: 18p11.21

Target Gene Details

• Entrez Gene ID: 65258
• Gene Name: metallophosphoesterase 1
• Gene Aliases: PGAP5
• Location: Chr.18:11883471-11908797 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MPPE1	NM_001242904.1			NP_001229833.1
	NM_001319154.1			NP_001306083.1
	NM_023075.5			NP_075563.3
	NR_040241.1
	NR_040242.3
	NR_040243.1
	XM_006722340.3			XP_006722403.1
	XM_006722341.3			XP_006722404.1
	XM_006722342.3			XP_006722405.1
	XM_006722343.3			XP_006722406.1
	XM_006722345.3			XP_006722408.1
	XM_006722346.2			XP_006722409.1
	XM_006722347.3			XP_006722410.1
	XM_006722348.2			XP_006722411.1
	XM_011525731.2			XP_011524033.1
	XM_011525732.1			XP_011524034.1
	XM_011525734.1			XP_011524036.1
	XM_017025920.1			XP_016881409.1
	XM_017025921.1			XP_016881410.1
	XM_017025922.1			XP_016881411.1
	XM_017025923.1			XP_016881412.1
	XM_017025924.1			XP_016881413.1
	XM_017025925.1			XP_016881414.1
	XM_017025926.1			XP_016881415.1
	XM_017025927.1			XP_016881416.1
	XM_017025928.1			XP_016881417.1
	XM_017025929.1			XP_016881418.1
	XM_017025930.1			XP_016881419.1
	XM_017025931.1	9	1196	XP_016881420.1
	AF289560.1			AAL55744.1
	AF363484.1			AAM00279.1
	AK021647.1			BAB13863.1
	AK023052.1	5	1086	BAB14378.1
	AK054639.1
	AK223450.1			BAD97170.1
	AK309948.1	9	1161
	AL833636.1
	AX775853.1			CAE11626.1
	BC002877.2			AAH02877.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057995	Chr.18:10626172 - 11923368 on Build GRCh38	Gain	CHMP1B MPPE1 MIR7153 SLC35G4 GNAL LINC01255 LOC101927410 MIR6788 PIEZO2
nsv833590	Chr.18:11757330 - 11924540 on Build GRCh38	Gain	CHMP1B MPPE1 GNAL

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

esterase

Gene Ontology Categories:

Process(es)

GPI anchor biosynthetic process
ER to Golgi vesicle-mediated transport

Function(s)

protein binding
phosphoric diester hydrolase activity
manganese ion binding
GPI anchor binding