Hs00626557_cn

• Gene Symbol: GLUL
• Assay Reference Genome Location: Chr.1:182383884 on build GRCh38
• Cytoband: 1q25.3

Target Gene Details

• Entrez Gene ID: 2752
• Gene Name: glutamate-ammonia ligase
• Gene Aliases: GLNS, GS, PIG43, PIG59
• Location: Chr.1:182378093-182392206 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLUL	NM_001033044.3	7	2184	NP_001028216.1
	NM_001033056.3	7	1886	NP_001028228.1
	NM_002065.6	8	2540	NP_002056.2
	XM_006711278.1	7	2247	XP_006711341.1
	AK301600.1
	AL161952.1	2	4005	CAB82304.1
	AY947343.1	7	1744
	BC011700.2	7	1752	AAH11700.1
	BC011852.2	7	1763	AAH11852.1
	BC018992.1	8	2103	AAH18992.1
	BC051726.1	7	2949	AAH51726.1
	BX537384.1	7	1768	CAD97626.1
	S70290.1	6	1643	AAB30693.1
	X59834.1	7	1752	CAA42495.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv548358	Chr.1:182110851 - 183151893 on Build GRCh38	Gain	SHCBP1L TEDDM1 LOC284648 LOC647070 LINC00272 GLUL RGS8 ZNF648 LINC01344 NPL DHX9 RGSL1 LAMC1 RNASEL RGS16 LOC105371644

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ligase

Gene Ontology Categories:

Process(es)

neurotransmitter uptake
glutamate catabolic process
glutamine biosynthetic process
cell proliferation
cellular amino acid biosynthetic process
cellular response to starvation
response to glucose
ammonia assimilation cycle
positive regulation of insulin secretion
positive regulation of epithelial cell proliferation
protein homooligomerization
positive regulation of synaptic transmission, glutamatergic

Function(s)

magnesium ion binding
glutamate decarboxylase activity
glutamate-ammonia ligase activity
protein binding
ATP binding
glutamate binding
manganese ion binding
identical protein binding
dynein light chain binding