Hs00643112_cn

• Gene Symbol: APOM
• Assay Reference Genome Location: Chr.6:31656495 on build GRCh38
• Cytoband: 6p21.33

Target Gene Details

• Entrez Gene ID: 55937
• Gene Name: apolipoprotein M
• Gene Aliases: G3a, HSPC336, NG20, apo-M
• Location: Chr.6:31652410-31658210 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOM	NM_001256169.1			NP_001243098.1
	NM_019101.2			NP_061974.2
	NR_045828.1
	XM_006715150.3			XP_006715213.1
	AA846749.1
	AF118393.3			AAD11443.2
	AF161454.1			AAF29014.1
	AJ245434.1			CAB51604.1
	BC020683.1			AAH20683.1
	BF344944.1
	BG564719.1
	CB054016.1
	CN428415.1

Target Gene Details

• Entrez Gene ID: 7917
• Gene Name: BCL2 associated athanogene 6
• Gene Aliases: BAG-6, BAT3, D6S52E, G3
• Location: Chr.6:31639028-31660900 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BAG6	XM_017011279.1			XP_016866768.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv462871	Chr.6:31607499 - 31664357 on Build GRCh38	Loss	C6orf47 PRRC2A AIF1 MIR6832 BAG6 SNORA38 APOM GPANK1
nsv1126749	Chr.6:31457323 - 32594423 on Build GRCh38	Deletion	STK19 PRRC2A HCG26 MCCD1 LY6G6D ATP6V1G2-DDX39B LOC101929163 LOC100287329 DDAH2 CFB LY6G6F PRRT1 DXO VARS GPANK1 C6orf25 SKIV2L AGER C4B SAPCD1 ZBTB12 NEU1 CSNK2B LY6G6C C2-AS1 LST1 BAG6 PBX2 SNORD84 PPT2-EGFL8 C4A SNORD117 LY6G6E ATF6B SAPCD1-AS1 PPT2 CYP21A2 EHMT2 TNF HLA-DRB6 C6orf10 MIR6832 SLC44A4 SNORA38 HLA-DRA RNF5 CYP21A1P MIR6833 C6orf47 MICB ATP6V1G2 HCP5 MSH5-SAPCD1 LOC100507547 HLA-DRB5 LOC102725068 FKBPL MIR1236 NCR3 SNORD48 NELFE HSPA1B VWA7 CLIC1 EGFL8 MSH5 HSPA1A C6orf48 C2 LSM2 LTA LY6G5C ABHD16A MIR6721 TNXB TNXA LY6G5B LTB GPSM3 NFKBIL1 MIR4646 NOTCH4 HSPA1L AIF1 DDX39B HLA-DRB1 SNORD52 BTNL2 APOM HCG23 AGPAT1 DDX39B-AS1
nsv1073969	Chr.6:31456422 - 33480523 on Build GRCh38	Deletion	STK19 PRRC2A HCG26 LOC101929163 DDAH2 VPS52 KIFC1 CFB PRRT1 CUTA DXO ZBTB22 GPANK1 COL11A2 HLA-DOA MIR219A1 TAPBP TAP2 HCG25 RXRB PHF1 SAPCD1 LY6G6C LST1 PBX2 SNORD84 HLA-DQB1-AS1 PPT2-EGFL8 HSD17B8 HLA-DPB2 HLA-DPA1 SNORD117 ZBTB9 PSMB9 EHMT2 MIR6832 RGL2 SNORA38 HLA-DRA CYP21A1P HLA-DQB2 C6orf47 MICB ATP6V1G2 HCP5 MSH5-SAPCD1 HLA-DRB5 LOC102725068 MIR1236 NCR3 SNORD48 HCG24 B3GALT4 NELFE SLC39A7 HSPA1B CLIC1 EGFL8 MSH5 HSPA1A C2 LSM2 LY6G5C ABHD16A MIR6873 LY6G5B GPSM3 NFKBIL1 NOTCH4 HSPA1L AIF1 DDX39B HLA-DRB1 APOM DAXX MCCD1 LY6G6D ATP6V1G2-DDX39B LOC100287329 LY6G6F VARS C6orf25 SKIV2L AGER C4B HLA-DQB1 ZBTB12 HLA-DMA NEU1 HLA-DQA1 CSNK2B C2-AS1 BAG6 WDR46 C4A MIR6834 PPP1R2P1 LY6G6E RPS18 ATF6B SAPCD1-AS1 PPT2 TAP1 CYP21A2 BRD2 TNF HLA-DRB6 C6orf10 MIR3135B SLC44A4 RING1 PSMB8 PFDN6 RNF5 MIR6833 LOC100507547 FKBPL VWA7 C6orf48 HLA-DOB LTA LOC100294145 MIR6721 MIR5004 TNXB TNXA HLA-DQA2 HLA-DPB1 HLA-DMB LTB SYNGAP1 MIR4646 SNORD52 BTNL2 PSMB8-AS1 HCG23 AGPAT1 DDX39B-AS1
dgv10403n54	Chr.6:31312324 - 32049763 on Build GRCh38	Loss	STK19 PRRC2A HCG26 MCCD1 LY6G6D ATP6V1G2-DDX39B LOC100287329 DDAH2 CFB LY6G6F DXO VARS GPANK1 C6orf25 SKIV2L C4B SAPCD1 ZBTB12 NEU1 CSNK2B LY6G6C HLA-B C2-AS1 LST1 BAG6 SNORD84 C4A SNORD117 LY6G6E SAPCD1-AS1 CYP21A2 EHMT2 TNF MIR6891 MIR6832 SLC44A4 SNORA38 CYP21A1P C6orf47 MICB ATP6V1G2 HCP5 MSH5-SAPCD1 LOC102725068 MIR1236 NCR3 SNORD48 MICA NELFE HSPA1B VWA7 CLIC1 MSH5 HSPA1A C6orf48 C2 LSM2 LTA LY6G5C ABHD16A TNXB TNXA LY6G5B LTB NFKBIL1 MIR4646 HSPA1L AIF1 DDX39B SNORD52 APOM DDX39B-AS1
nsv1112900	Chr.6:31455323 - 33480423 on Build GRCh38	Deletion	STK19 PRRC2A HCG26 LOC101929163 DDAH2 VPS52 KIFC1 CFB PRRT1 CUTA DXO ZBTB22 GPANK1 COL11A2 HLA-DOA MIR219A1 TAPBP TAP2 HCG25 RXRB PHF1 SAPCD1 LY6G6C LST1 PBX2 SNORD84 HLA-DQB1-AS1 PPT2-EGFL8 HSD17B8 HLA-DPB2 HLA-DPA1 SNORD117 ZBTB9 PSMB9 EHMT2 MIR6832 RGL2 SNORA38 HLA-DRA CYP21A1P HLA-DQB2 C6orf47 MICB ATP6V1G2 HCP5 MSH5-SAPCD1 HLA-DRB5 LOC102725068 MIR1236 NCR3 SNORD48 HCG24 B3GALT4 NELFE SLC39A7 HSPA1B CLIC1 EGFL8 MSH5 HSPA1A C2 LSM2 LY6G5C ABHD16A MIR6873 LY6G5B GPSM3 NFKBIL1 NOTCH4 HSPA1L AIF1 DDX39B HLA-DRB1 APOM DAXX MCCD1 LY6G6D ATP6V1G2-DDX39B LOC100287329 LY6G6F VARS C6orf25 SKIV2L AGER C4B HLA-DQB1 ZBTB12 HLA-DMA NEU1 HLA-DQA1 CSNK2B C2-AS1 BAG6 WDR46 C4A MIR6834 PPP1R2P1 LY6G6E RPS18 ATF6B SAPCD1-AS1 PPT2 TAP1 CYP21A2 BRD2 TNF HLA-DRB6 C6orf10 MIR3135B SLC44A4 RING1 PSMB8 PFDN6 RNF5 MIR6833 LOC100507547 FKBPL VWA7 C6orf48 HLA-DOB LTA LOC100294145 MIR6721 MIR5004 TNXB TNXA HLA-DQA2 HLA-DPB1 HLA-DMB LTB SYNGAP1 MIR4646 SNORD52 BTNL2 PSMB8-AS1 HCG23 AGPAT1 DDX39B-AS1
dgv10404n54	Chr.6:31312550 - 32516591 on Build GRCh38	Loss	STK19 PRRC2A HCG26 MCCD1 LY6G6D ATP6V1G2-DDX39B LOC101929163 LOC100287329 DDAH2 CFB LY6G6F PRRT1 DXO VARS GPANK1 C6orf25 SKIV2L AGER C4B SAPCD1 ZBTB12 NEU1 CSNK2B LY6G6C HLA-B C2-AS1 LST1 BAG6 PBX2 SNORD84 PPT2-EGFL8 C4A SNORD117 LY6G6E ATF6B SAPCD1-AS1 PPT2 CYP21A2 EHMT2 TNF C6orf10 MIR6891 MIR6832 SLC44A4 SNORA38 HLA-DRA RNF5 CYP21A1P MIR6833 C6orf47 MICB ATP6V1G2 HCP5 MSH5-SAPCD1 LOC100507547 LOC102725068 FKBPL MIR1236 NCR3 SNORD48 MICA NELFE HSPA1B VWA7 CLIC1 EGFL8 MSH5 HSPA1A C6orf48 C2 LSM2 LTA LY6G5C ABHD16A MIR6721 TNXB TNXA LY6G5B LTB GPSM3 NFKBIL1 MIR4646 NOTCH4 HSPA1L AIF1 DDX39B SNORD52 BTNL2 APOM HCG23 AGPAT1 DDX39B-AS1
nsv1161370	Chr.6:31600692 - 31714252 on Build GRCh38	Deletion	PRRC2A MIR6832 BAG6 LY6G5C ABHD16A SNORA38 LY6G6F LY6G5B GPANK1 C6orf47 LY6G6E MIR4646 AIF1 APOM CSNK2B
nsv830627	Chr.6:31528437 - 31692173 on Build GRCh38	Loss	PRRC2A TNF MIR6832 MCCD1 ATP6V1G2-DDX39B LOC100287329 SNORA38 GPANK1 C6orf47 ATP6V1G2 NCR3 CSNK2B LST1 LTA BAG6 SNORD84 LY6G5C ABHD16A LY6G5B LTB SNORD117 NFKBIL1 AIF1 DDX39B APOM DDX39B-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

apolipoprotein, transfer/carrier protein, chaperone

Gene Ontology Categories:

Process(es)

retinoid metabolic process
response to glucose
cholesterol efflux
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
negative regulation of plasma lipoprotein particle oxidation
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
cellular oxidant detoxification
kidney development
immune system process
ubiquitin-dependent protein catabolic process
transport
synaptonemal complex assembly
spermatogenesis
brain development
embryo development
covalent chromatin modification
internal peptidyl-lysine acetylation
cell differentiation
lung development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of proteolysis
protein stabilization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
tail-anchored membrane protein insertion into ER membrane
positive regulation of ERAD pathway
maintenance of unfolded protein involved in ERAD pathway
protein localization to cytosolic proteasome complex involved in ERAD pathway

Function(s)

lipid transporter activity
phospholipid binding
antioxidant activity
protein binding
Hsp70 protein binding
polyubiquitin binding
ubiquitin protein ligase binding
ribosome binding
misfolded protein binding
proteasome binding
ubiquitin-specific protease binding