Hs00680036_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130359444 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Overlaps Exon 4 - Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	POTEF CCDC115 CYP4F62P MZT2B CCDC74B FAR2P2 PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	POTEF CCDC115 FAR2P1 MZT2B CCDC74B PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
nsv583133	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	CCDC115 PTPN18 IMP4
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	CCDC115 MZT2B PTPN18 SMPD4 NOC2LP1 TUBA3E IMP4
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	POTEF CCDC115 FAR2P1 MZT2B CCDC74B PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	CCDC115 MZT2B CCDC74B PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	CCDC115 MZT2B CCDC74B PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	POTEI CCDC115 CYP4F62P MZT2B PTPN18 SMPD4 TISP43 LOC107985778 CFC1 CFC1B FAR2P2 NOC2LP1 LOC646743 TUBA3E IMP4 POTEJ
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	POTEF CCDC115 FAR2P1 MZT2B CCDC74B PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
dgv7080n54	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	CCDC115 MZT2B PTPN18 NOC2LP1 TUBA3E IMP4
nsv459274	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	CCDC115 MZT2B LOC101927881 LOC101927924 PTPN18 SMPD4 RAB6C MED15P9 POTEF RAB6C-AS1 FAR2P1 LOC389033 CCDC74B LOC151121 NOC2LP1 TUBA3E IMP4
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	CCDC115 CYP4F62P FAR2P2 PTPN18 IMP4
esv3592451	Chr.2:130282861 - 130401532 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	CCDC115 MZT2B LOC101927924 PTPN18 SMPD4 RAB6C MED15P9 POTEF RAB6C-AS1 FAR2P1 LOC389033 CCDC74B NOC2LP1 TUBA3E IMP4
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	NOC2LP2 MIR4784 MZT2B ZNF806 CYP4F30P PTPN18 MED15P9 GPR148 LOC100507460 NOC2LP1 LOC646743 TUBA3E GPR39 IMP4 POTEKP POTEI TUBA3D CYP4F62P LOC101927924 RAB6C ARHGEF4 POTEF LOC107985778 CFC1 WTH3DI RAB6C-AS1 C2orf27B FAR2P1 LOC389033 LOC440910 CCDC115 LOC150776 SMPD4 POTEE FAM168B CCDC74B FAR2P2 LINC01087 MIR663B MZT2A LINC01120 AMER3 C2orf27A TISP43 ANKRD30BL CFC1B FAM201B PLEKHB2 CCDC74A POTEJ
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	POTEI CCDC115 CYP4F62P MZT2B PTPN18 SMPD4 MED15P9 POTEF CCDC74B FAR2P2 NOC2LP1 TUBA3E IMP4
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	POTEF CCDC115 MZT2B CCDC74B PTPN18 SMPD4 NOC2LP1 TUBA3E MED15P9 IMP4
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CCDC115 MZT2B CYP4F30P PTPN18 SMPD4 MED15P9 GPR148 CCDC74B FAR2P2 NOC2LP1 LOC646743 TUBA3E IMP4 AMER3 POTEI CYP4F62P LOC101927924 RAB6C TISP43 ARHGEF4 POTEF LOC107985778 CFC1 CFC1B RAB6C-AS1 FAR2P1 LOC389033 POTEJ

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding